Key Laboratory of Green Prevention and Control on Fruits and Vegetables in South China, Ministry of Agriculture and Rural Affairs, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Innovative Institute for Plant Health, Zhongkai University of Agriculture and Engineering, Guangzhou, P.R. China.
J Cell Physiol. 2024 Oct;239(10):e30974. doi: 10.1002/jcp.30974. Epub 2023 Feb 15.
Bacillus species act as plant growth-promoting rhizobacteria (PGPR) that can produce a large number of bioactive metabolites. Bacillaene, a linear polyketide/nonribosomal peptide produced by Bacillus strains, is synthesized by the trans-acyltransferase polyketide synthetase. The complexity of the chemical structure, particularity of biosynthesis, potent bioactivity, and the important role of competition make Bacillus an ideal antibiotic weapon to resist other microbes and maintain the optimal rhizosphere environment. This review provides an updated view of the structural features, biological activity, biosynthetic regulators of biosynthetic pathways, and the important competitive role of bacillaene during Bacillus survival.
芽孢杆菌作为植物促生根际细菌 (PGPR)，可以产生大量的生物活性代谢物。芽孢杆菌产生的线性聚酮/非核糖体肽芽孢烯，由反酰基转移酶聚酮合酶合成。其化学结构的复杂性、生物合成的特殊性、强大的生物活性以及在竞争中发挥的重要作用，使芽孢杆菌成为抵抗其他微生物和维持最佳根际环境的理想抗生素武器。本文综述了芽孢烯的结构特征、生物活性、生物合成途径的生物合成调控因子，以及在芽孢杆菌生存过程中的重要竞争作用。
