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中效全氟辛烷作为非常复杂视网膜脱离术后挽救性眼内填塞的应用:解剖学和功能结果。

MEDIUM-TERM PERFLUORO-N-OCTANE AS RESCUE POSTOPERATIVE TAMPONADE FOR VERY COMPLEX RETINAL DETACHMENTS: ANATOMICAL AND FUNCTIONAL OUTCOMES.

机构信息

Ratan Jyoti Netralaya, India.

Calderdale Huddersfield Foundation NHS Trust Hospital, UK; and.

出版信息

Retina. 2023 Jun 1;43(6):905-912. doi: 10.1097/IAE.0000000000003763.

DOI:10.1097/IAE.0000000000003763
PMID:36791344
Abstract

PURPOSE

To report the anatomical and functional outcomes of medium-term perfluoro-n-octane (PFO) tamponade as a rescue procedure in very complex retinal detachments (RDs).

METHODS

We reviewed the case records of 35 consecutive patients who underwent vitrectomy for very complex RDs due to diverse etiologies. The surgical complexity was so graded because of the intraoperative failure to ascertain complete retinal reattachment; perfluoro-n-octane was used as rescue tamponade for 2 to 4 weeks. The second intervention included additional membrane peeling, retinectomy, endophotocoagulation, and gas/silicone oil tamponade. The minimum follow-up was 3 months after the final intervention: the primary outcome was retinal reattachment and the secondary outcome was change in best-corrected visual acuity (BCVA).

RESULTS

The most common presentations were severe trauma with retinal incarceration, preretinal and subretinal hemorrhage, or chronic/recurrent RDs with anterior proliferative vitreoretinopathy. Preoperative BCVA was ≤counting fingers in 31 (88.6%) patients. Complete retinal attachment without any tamponade was achieved in 33 (94.3%) eyes. best-corrected visual acuity improved in 30 (85.7%) eyes: 16 (45.7%) had BCVA ≥20/200 and 21 (60%) regained ambulatory vision (≥5/200). Two eyes developed keratopathy, and four needed antiglaucoma medications.

CONCLUSION

We achieved excellent anatomical outcomes and acceptable functional outcomes in nearly inoperable RDs with few side effects. Medium-term perfluoro-n-octane tamponade can be used as a salvage procedure in very complex RDs where intraoperative reattachment cannot be ensured.

摘要

目的

报告中短期全氟萘烷(PFO)作为一种救援程序在非常复杂的视网膜脱离(RD)中的解剖和功能结果。

方法

我们回顾了 35 例连续接受玻璃体切除术治疗的非常复杂 RD 患者的病例记录,这些 RD 患者的病因各不相同。由于术中无法确定完全视网膜复位,因此将手术的复杂性分级;使用全氟萘烷作为 2 至 4 周的救援性填塞。第二次干预包括额外的膜剥除、视网膜切除术、眼内光凝和气体/硅油填塞。最后一次干预后至少随访 3 个月:主要结果是视网膜复位,次要结果是最佳矫正视力(BCVA)的变化。

结果

最常见的表现是严重创伤伴视网膜嵌顿、视网膜前和视网膜下出血,或慢性/复发性 RD 伴前部增生性玻璃体视网膜病变。术前 BCVA 为≤31 只(88.6%)患者。33 只(94.3%)眼实现了无任何填塞的完全视网膜附着。30 只(85.7%)眼的最佳矫正视力提高:16 只(45.7%)BCVA≥20/200,21 只(60%)恢复了可走动视力(≥5/200)。两只眼发生了角膜病变,四只眼需要抗青光眼药物。

结论

我们在几乎无法手术的 RD 中获得了极好的解剖学结果和可接受的功能结果,且副作用较少。中短期全氟萘烷填塞可作为术中无法确保复位的非常复杂 RD 的挽救性手术。

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