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牙龈注射透明质酸后单侧硬腭坏死

Unilateral hard palate necrosis following gingival injections with hyaluronic acid.

作者信息

Vaquero Martinez Pablo, Guarro Marzoa Ingrid, de Pablo Cuenca-Garcia Alba, Bescos Atin Coro

机构信息

Oral and Maxillofacial Surgery, Vall d'Hebron Hospital Campus, Barcelona, Spain

Oral and Maxillofacial Surgery, Vall d'Hebron Hospital Campus, Barcelona, Spain.

出版信息

BMJ Case Rep. 2023 Feb 15;16(2):e254599. doi: 10.1136/bcr-2023-254599.

DOI:10.1136/bcr-2023-254599
PMID:36792144
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9933658/
Abstract

Hyaluronic acid (HA) injections into the oral mucosa have proven to be effective as a non-invasive method for the reconstruction of interproximal papillary defects in aesthetic areas. Despite being a minimally invasive and safe technique, certain side effects may occur after treatment.We report the first case of a patient with unilateral necrosis of the mucosa of the hard palate after HA filling in the maxillary anterior gingiva. Familiarity with these events and competent knowledge of the anatomy is essential to avoid complications, achieve and offer adequate treatment and good results to our patients.

摘要

向口腔黏膜注射透明质酸(HA)已被证明是一种有效的非侵入性方法,可用于美学区域邻面乳头缺损的重建。尽管这是一种微创且安全的技术,但治疗后仍可能出现某些副作用。我们报告了第一例在上颌前牙龈进行HA填充后硬腭黏膜单侧坏死的患者。熟悉这些情况并掌握相关解剖知识对于避免并发症、为患者提供充分的治疗并取得良好效果至关重要。

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本文引用的文献

1
Distal Internal Maxillary Artery Occlusion with Palatal Necrosis following Cheek Injection with Calcium Hydroxylapatite.注射羟基磷灰石钙丰颊后发生腭部坏死伴上颌动脉远端闭塞
Plast Reconstr Surg Glob Open. 2022 Mar 7;10(3):e4164. doi: 10.1097/GOX.0000000000004164. eCollection 2022 Mar.
2
Postanaesthetic Aseptic Palatal Necrosis - A Case Report.麻醉后无菌性腭部坏死——病例报告
Ann Maxillofac Surg. 2021 Jan-Jun;11(1):173-175. doi: 10.4103/ams.ams_289_20. Epub 2021 Jul 24.
3
Is interdental papilla filling using hyaluronic acid a stable approach to treat black triangles? A systematic review.使用透明质酸进行牙间乳头填充治疗黑三角是否可行?系统评价。
J Esthet Restor Dent. 2021 Apr;33(3):458-465. doi: 10.1111/jerd.12694. Epub 2020 Dec 17.
4
Interdental papilla reconstruction using injectable hyaluronic acid: A 6 month prospective longitudinal clinical study.应用注射用透明质酸进行牙间乳头重建:一项 6 个月前瞻性纵向临床研究。
J Esthet Restor Dent. 2021 Apr;33(3):531-537. doi: 10.1111/jerd.12680. Epub 2020 Nov 10.
5
Biological molecules in dental applications: hyaluronic acid as a companion biomaterial for diverse dental applications.牙科应用中的生物分子:透明质酸作为多种牙科应用的辅助生物材料。
Heliyon. 2020 Apr 6;6(4):e03722. doi: 10.1016/j.heliyon.2020.e03722. eCollection 2020 Apr.
6
Soft-tissue Filler-associated Blindness: A Systematic Review of Case Reports and Case Series.软组织填充剂相关失明:病例报告和病例系列的系统评价
Plast Reconstr Surg Glob Open. 2019 Apr 2;7(4):e2173. doi: 10.1097/GOX.0000000000002173. eCollection 2019 Apr.
7
This month's guideline: The Use of Hyaluronidase in Aesthetic Practice (v2.4).本月指南:透明质酸酶在美容实践中的应用(第2.4版)
J Clin Aesthet Dermatol. 2018 Jun;11(6):E61-E68. Epub 2018 Jun 1.
8
Biotechnological production of hyaluronic acid: a mini review.透明质酸的生物技术生产:一篇综述
3 Biotech. 2016 Jun;6(1):67. doi: 10.1007/s13205-016-0379-9. Epub 2016 Feb 15.
9
Adverse reaction after hyaluronan injection for minimally invasive papilla volume augmentation. A report on two cases.透明质酸注射用于微创乳头体积增大后的不良反应。两例报告。
Clin Oral Implants Res. 2017 Jul;28(7):871-876. doi: 10.1111/clr.12892. Epub 2016 Jun 1.
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Complications following injection of soft-tissue fillers.注射软组织填充剂后的并发症。
Aesthet Surg J. 2013 Aug 1;33(6):862-77. doi: 10.1177/1090820X13493638. Epub 2013 Jul 3.