Mabey D C, Wall R A, Bello C S
Medical Research Council Laboratories, Fajara, the Gambia.
Genitourin Med. 1987 Oct;63(5):312-5. doi: 10.1136/sti.63.5.312.
The aetiology of genital ulceration was studied in 104 unselected patients (94 men, 10 women) attending a sexually transmitted disease (STD) clinic in the Gambia. Chancroid was diagnosed in 54 (52%), syphilis in 23 (22%), lymphogranuloma venereum (LGV) in seven (7%), and herpes in six (6%). In 28 (27%) patients no diagnosis was reached. Ten (10%) patients were found to have both chancroid and syphilis, three (3%) had both LGV and syphilis, and one (1%) had both herpes and syphilis. Trimethoprim 160 mg and sulphamethoxazole 800 mg twice daily for one week was found to be effective in the treatment of chancroid. This regimen with a single intramuscular injection of benzathine penicillin 2.4 MIU is recommended for the treatment of genital ulcers in Gambian health centres without laboratory facilities.
在冈比亚一家性传播疾病（STD）诊所对104名未经挑选的患者（94名男性，10名女性）的生殖器溃疡病因进行了研究。软下疳确诊54例（52%），梅毒23例（22%），性病性淋巴肉芽肿（LGV）7例（7%），疱疹6例（6%）。28例（27%）患者未明确诊断。10例（10%）患者同时患有软下疳和梅毒，3例（3%）同时患有LGV和梅毒，1例（1%）同时患有疱疹和梅毒。发现每日两次服用160毫克甲氧苄啶和800毫克磺胺甲恶唑，持续一周，对治疗软下疳有效。对于冈比亚没有实验室设施的卫生中心，建议采用该方案并单次肌内注射240万单位苄星青霉素来治疗生殖器溃疡。
