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坦桑尼亚西北部梅毒及性传播疾病综合征的基于人群的研究。1. 患病率和发病率。

A population-based study of syphilis and sexually transmitted disease syndromes in north-western Tanzania. 1. Prevalence and incidence.

作者信息

Mosha F, Nicoll A, Barongo L, Borgdorff M, Newell J, Senkoro K, Grosskurth H, Changalucha J, Klokke A, Killewo J

机构信息

National Institute for Medical Research, Mwanza, Tanzania.

出版信息

Genitourin Med. 1993 Dec;69(6):415-20. doi: 10.1136/sti.69.6.415.

Abstract

OBJECTIVE

To determine the prevalence of syphilis and the prevalence and incidence of self-reported STD syndromes in the population of Mwanza Region, North-Western Tanzania.

METHODS

A population-based random cluster sample survey, stratified by rural, roadside or urban residence, of 4173 individuals aged 15-54 years was performed in 1990-91. The seroprevalence of syphilis (using TPHA and RPR) and the prevalence and incidence of self-reported genital ulcer syndrome (GUS) and genital discharge syndrome (GDS) were determined.

RESULTS

Active syphilis was detected in 9% of the adult population, while 15% had serological evidence of past or current infection. Seroprevalence was significantly lower in the rural than in the roadside and urban populations, but there was little difference between men and women. Amongst men, a history of GDS was reported by 28%, and a history of GUS by 14%, with point prevalences of 2.3% and 1.3% respectively. Annual incidence among men were 6.8% for GDS and 3.6% for GUS. Women reported these conditions less frequently. There was little difference between the strata in the prevalence or incidence of reported STD syndromes.

CONCLUSION

Sexually transmitted diseases represent a major public health problem in both the rural and urban populations of Mwanza Region.

摘要

目的

确定坦桑尼亚西北部姆万扎地区人群中梅毒的患病率以及自我报告的性传播感染综合征的患病率和发病率。

方法

1990 - 1991年,在15 - 54岁的人群中开展了一项基于人群的随机整群抽样调查,按农村、路边或城市居住情况进行分层,共纳入4173人。确定梅毒的血清学患病率(采用梅毒螺旋体血凝试验和快速血浆反应素环状卡片试验)以及自我报告的生殖器溃疡综合征(GUS)和生殖器分泌物综合征(GDS)的患病率和发病率。

结果

在成年人群中,9%检测到活动性梅毒,而15%有既往或当前感染的血清学证据。农村地区的血清学患病率显著低于路边和城市人群,但男女之间差异不大。在男性中,28%报告有GDS病史,14%报告有GUS病史,现患率分别为2.3%和1.3%。男性中GDS的年发病率为6.8%,GUS为3.6%。女性报告这些情况的频率较低。报告的性传播感染综合征的患病率或发病率在各层之间差异不大。

结论

性传播疾病是姆万扎地区农村和城市人群中的一个主要公共卫生问题。

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