Biosciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, Devon, UK.
Adv Exp Med Biol. 2023;1404:253-268. doi: 10.1007/978-3-031-22997-8_13.
During periods that are not conducive for growth or when facing stressful conditions, Vibrios enter a dormant state called the Viable But Non-Culturable (VBNC) state. In this chapter, I will analyse the role of the VBNC state in Vibrio species survival and pathogenesis and the molecular mechanisms regulating this complex phenomenon. I will emphasise some of the novel findings that make studying the VBNC state now more exciting than ever and its significance in the epidemiology of these pathogens and critical role in food safety.
在不利于生长或面临压力条件时，弧菌会进入休眠状态，称为“可生存但非可培养（VBNC）”状态。在本章中，我将分析 VBNC 状态在弧菌物种生存和发病机制中的作用，以及调节这一复杂现象的分子机制。我将强调一些新的发现，这些发现使研究 VBNC 状态比以往任何时候都更加令人兴奋，以及它在这些病原体的流行病学中的重要性和在食品安全中的关键作用。
