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集胞藻 PCC 6803 亚系 GT-T 的基因组序列及其对 PCC 6803 亚系进化的启示。

The genome sequence of Synechocystis sp. PCC 6803 substrain GT-T and its implications for the evolution of PCC 6803 substrains.

机构信息

Department of Life Sciences/Molecular Plant Biology, University of Turku, Finland.

Institute of Microbiology of the Czech Academy of Sciences, Třeboň, Czech Republic.

出版信息

FEBS Open Bio. 2023 Apr;13(4):701-712. doi: 10.1002/2211-5463.13576. Epub 2023 Feb 21.

DOI:10.1002/2211-5463.13576
PMID:36792971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10068330/
Abstract

Synechocystis sp. PCC 6803 is a model cyanobacterium, glucose-tolerant substrains of which are commonly used as laboratory strains. In recent years, it has become evident that 'wild-type' strains used in different laboratories show some differences in their phenotypes. We report here the chromosome sequence of our Synechocystis sp. PCC 6803 substrain, named substrain GT-T. The chromosome sequence of GT-T was compared to those of two other commonly used laboratory substrains, GT-S and PCC-M. We identified 11 specific mutations in the GT-T substrain, whose physiological consequences are discussed. We also provide an update on evolutionary relationships between different Synechocystis sp. PCC 6803 substrains.

摘要

集胞藻 PCC 6803 是一种模式蓝藻，其耐葡萄糖的亚系通常被用作实验室菌株。近年来，人们已经清楚地认识到，不同实验室使用的“野生型”菌株在表型上存在一些差异。我们在此报告我们的集胞藻 PCC 6803 亚系 GT-T 的染色体序列。GT-T 的染色体序列与另外两个常用的实验室亚系 GT-S 和 PCC-M 进行了比较。我们在 GT-T 亚系中鉴定出 11 个特定的突变，讨论了其生理后果。我们还提供了不同集胞藻 PCC 6803 亚系之间进化关系的最新信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10068330/be61cbbb0fe3/FEB4-13-701-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10068330/f7b0fe14ca26/FEB4-13-701-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10068330/4c0bc345850e/FEB4-13-701-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10068330/508a4e03a295/FEB4-13-701-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10068330/be61cbbb0fe3/FEB4-13-701-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10068330/f7b0fe14ca26/FEB4-13-701-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10068330/4c0bc345850e/FEB4-13-701-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10068330/508a4e03a295/FEB4-13-701-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca53/10068330/be61cbbb0fe3/FEB4-13-701-g003.jpg

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