Chang Chia Ning, Shen Chiung Chyi
Department of Neurosurgery, Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan.
Front Surg. 2023 Jan 30;9:1021680. doi: 10.3389/fsurg.2022.1021680. eCollection 2022.
Spindle cell oncocytoma (SCO) of the pituitary gland is increasingly established with improvements in histological and immunohistochemical examination. However, the diagnosis was often mistaken based on imaging studies and nonspecific clinical manifestations.
This case is presented to provide an overview of the characteristics of the rare tumor as well as to demonstrate the difficulties in diagnosis and current treatments.
The pathogenesis of SCO remains unclear, and a possible origin was described. Further research is needed to optimize pre-operative diagnosis and surgical strategy.
SCO should be considered when images indicate some features. Gross total resection (GTR) after surgery seems to have better long-term tumor control, and radiotherapy may help decrease tumor progression in patients with non-GTR. Regular follow-up is advised because of the higher recurrence rate.
随着组织学和免疫组织化学检查技术的进步，垂体梭形细胞嗜酸细胞瘤（SCO）越来越多地被确诊。然而，基于影像学研究和非特异性临床表现，其诊断常被误诊。
本文通过该病例展示这种罕见肿瘤的特征，以及诊断难点和当前的治疗方法。
SCO的发病机制尚不清楚，并描述了一种可能的起源。需要进一步研究以优化术前诊断和手术策略。
当影像学显示某些特征时应考虑SCO。手术全切（GTR）似乎能更好地实现肿瘤的长期控制，对于未实现GTR的患者，放疗可能有助于降低肿瘤进展。鉴于复发率较高，建议定期随访。
