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心力衰竭患者生活质量低下的预测因素及其与药物依从性的相关性:改善医疗保健及随访的研究发现

Predictors to Poor Quality of Life Among Patients with Heart Failure and Its Correlation with Their Medication Adherence: Finding for Healthcare Improvement and Follow-Up.

作者信息

Alkubati Sameer A, Aleyadah Homoud Khaled, Alboliteeh Mohammad, Alharbi Abdulhafith, Alsaif Bandar, Alshammari Bushra, Balawi Anas

机构信息

Department of Medical Surgical Nursing, College of Nursing, University of Hail, Hail, Saudi Arabia.

Department of Nursing, Faculty of Medicine and Health Sciences, Hodeidah University, Hodeidah, Yemen.

出版信息

Patient Prefer Adherence. 2024 Dec 14;18:2545-2557. doi: 10.2147/PPA.S503087. eCollection 2024.

Abstract

BACKGROUND

Understanding medication adherence and its relationship with quality of life (QoL) is essential for improving health outcomes in patients with heart failure (HF).

OBJECTIVE

This study aimed to investigate the predictors of poor quality of life and its relationship with medication adherence among patients with heart failure.

METHODS

A cross-sectional correlational study was performed on 229 patients with HF receiving care at the Cardiac Center of King Salman Specialist Hospital from March to June 2024. Data were collected using a structured questionnaire comprising patient demographics, the Minnesota Living with Heart Failure Questionnaire (MLHFQ) to assess QoL, and the General Medication Adherence Scale (GMAS) to measure medication adherence.

RESULTS

The mean medication adherence score among patients with heart HF was 17.53 ± 6.94. The level of adherence was moderate among most patients (47.2%), high (29.7%), and poor (23.1%). Regarding QoL, the mean total score for overall QoL was 42.16 ± 20.53. Specifically, the mean scores were 15.24 ± 8.65 and 10.53 ± 5.82 for the physical and emotional dimensions of QoL, respectively. More than half of the patients experienced poor QoL, while moderate QoL was observed in 31.9% and good QoL in 17% of patients. Furthermore, there were moderate negative correlations between medication adherence and physical QoL (r= -0.51), emotional QoL (r = -0.59), and overall QoL (r = -0.59), all of which were statistically significant (p <0.001).

CONCLUSION

Moderate-to-poor levels of medication adherence and QoL were found among HF patients receiving care in Hail City. Therefore, interventions to improve medication adherence among patients with HF must be prioritized to enhance health outcomes and QoL. It is also crucial to address the factors that negatively influence medication adherence to overcome the barriers that hinder optimal medication adherence.

摘要

背景

了解药物依从性及其与生活质量(QoL)的关系对于改善心力衰竭(HF)患者的健康结局至关重要。

目的

本研究旨在调查心力衰竭患者生活质量差的预测因素及其与药物依从性的关系。

方法

2024年3月至6月,对在沙特国王萨勒曼专科医院心脏中心接受治疗的229例心力衰竭患者进行了一项横断面相关性研究。使用结构化问卷收集数据,该问卷包括患者人口统计学信息、用于评估生活质量的明尼苏达心力衰竭生活问卷(MLHFQ)以及用于测量药物依从性的一般药物依从性量表(GMAS)。

结果

心力衰竭患者的平均药物依从性得分为17.53±6.94。大多数患者的依从水平为中等(47.2%)、高(29.7%)和差(23.1%)。关于生活质量,总体生活质量的平均总分为42.16±20.53。具体而言,生活质量的身体维度和情感维度的平均得分分别为15.24±8.65和10.53±5.82。超过一半的患者生活质量差,而31.9%的患者生活质量中等,17%的患者生活质量良好。此外,药物依从性与身体生活质量(r=-0.51)、情感生活质量(r=-0.59)和总体生活质量(r=-0.59)之间存在中度负相关,所有这些均具有统计学意义(p<0.001)。

结论

在海伊市接受治疗的心力衰竭患者中发现药物依从性和生活质量处于中度至较差水平。因此,必须优先采取干预措施来提高心力衰竭患者的药物依从性,以改善健康结局和生活质量。解决对药物依从性产生负面影响的因素以克服阻碍最佳药物依从性的障碍也至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c75a/11656328/822ca7d10374/PPA-18-2545-g0001.jpg

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