Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, Tanjong Malim, Perak, Malaysia.
Department of Pure and Industrial Chemistry, Faculty Natural and Applied Science, Umaru Musa Yar'adua University, Katsina, Nigeria.
Nat Prod Res. 2024 Feb-Mar;38(4):629-633. doi: 10.1080/14786419.2023.2180507. Epub 2023 Feb 15.
This study was designed to examine the essential oils compositions of Siebold and Fern.-Vill. growing in Malaysia. The essential oils were achieved by hydrodistillation and fully characterized by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). The study identified 17 and 19 components from the leaf oils from (80.7%) and (81.5%), respectively. The major components of oil were β-selinene (30.8%), β-calacorene (11.3%), tridecanal (7.6%), isophytol (4.8%) and β-eudesmol (4.5%); whereas in oil gave β-caryophyllene (27.8%), caryophyllene oxide (12.8%), α-cadinol (6.3%), ()-nerolidol (5.7%), β-selinene (5.5%) and tridecanal (5.0%). Anticholinesterase activity was evaluated using Ellman method. The essential oils showed moderate inhibitory activity on acetylcholinesterase and butyrylcholinesterase assays. Our findings demonstrate that the essential oil could be very useful for the characterization, pharmaceutical, and therapeutic applications of the essential oil from the genus .
本研究旨在研究马来西亚产 Siebold 和 Fern.-Vill. 的精油成分。精油通过水蒸馏法获得，并通过气相色谱（GC-FID）和气相色谱-质谱联用（GC-MS）进行全面表征。研究从叶片油中分别鉴定出 17 种和 19 种成分，占（80.7%）和（81.5%）。油的主要成分是 β-瑟林烯（30.8%）、β-卡诺醇（11.3%）、十三醛（7.6%）、异植物醇（4.8%）和 β-艾杜醇（4.5%）；而油中 β-石竹烯（27.8%）、石竹烯氧化物（12.8%）、α-杜松醇（6.3%）、（）-橙花叔醇（5.7%）、β-瑟林烯（5.5%）和十三醛（5.0%）含量较高。采用 Ellman 法评价了其抗胆碱酯酶活性。结果表明，精油对乙酰胆碱酯酶和丁酰胆碱酯酶均有一定的抑制作用。本研究结果表明，该精油可用于该属植物精油的特征描述、药物和治疗应用。
