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海拔2800米处居住的厄瓜多尔孕妇的铁状态:与婴儿铁状态的关系。

Iron status in Ecuadorian pregnant women living at 2,800 m altitude: relationship with infant iron status.

作者信息

Yepez R, Calle A, Galan P, Estevez E, Davila M, Estrella R, Masse-Raimbault A M, Hercberg S

机构信息

Laboratorio de Investigaciones de Bioquimica, Facultad de Ciencias Medicas de Quito (Ecuador), Paris, France.

出版信息

Int J Vitam Nutr Res. 1987;57(3):327-32.

PMID:3679705
Abstract

An evaluation of iron status was performed in 84 pregnant women at delivery (and in cord blood from their newborn) and in a control group of 32 menstruating women living in Quito (2800 m altitude). Anemia as defined according to the WHO references adjusted to altitude was observed in 46% of pregnant women. Iron deficiency was defined as the combination of a low serum ferritin level (12 micrograms/l or less) and a low transferrin saturation percentage (less than 16%). A moderate elevation in the serum ferritin concentration (between 13 and 50 micrograms/l) associated with low transferrin saturation indicated iron deficiency in an inflammatory context. Iron deficiency was present in 46% of pregnant women. Anemia was associated with iron deficiency in 59% of cases. A correlation between maternal and cord blood hemoglobin was found and some iron parameters in cord blood were related to maternal iron status, and especially to maternal iron stores assessed by serum ferritin concentration.

摘要

对84名孕妇在分娩时(以及她们新生儿的脐带血)和32名居住在基多(海拔2800米)的月经周期正常女性组成的对照组进行了铁状态评估。根据根据海拔调整后的世界卫生组织参考标准定义,46%的孕妇存在贫血。缺铁定义为血清铁蛋白水平低(12微克/升或更低)和转铁蛋白饱和度百分比低(低于16%)。血清铁蛋白浓度适度升高(13至50微克/升之间)且转铁蛋白饱和度低表明在炎症背景下存在缺铁。46%的孕妇存在缺铁。59%的病例中贫血与缺铁相关。发现母体血红蛋白与脐带血血红蛋白之间存在相关性,脐带血中的一些铁参数与母体铁状态有关,尤其是与通过血清铁蛋白浓度评估的母体铁储备有关。

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Iron status in Ecuadorian pregnant women living at 2,800 m altitude: relationship with infant iron status.海拔2800米处居住的厄瓜多尔孕妇的铁状态:与婴儿铁状态的关系。
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