Tao J B, Wan B B, Chen J H, Jia J W, Cheng H, Lou L Q, Luo S Y
Yiwu Center for Disease Control and Prevention, Yiwu 322000, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2023 Feb 6;57(2):286-292. doi: 10.3760/cma.j.cn112150-20220829-00853.
With the determination of the whole genome sequence of varicella-zoster virus (VZV) virus, the successful breakthrough of infectious cloning technology of VZV, and the emergence of effective preventive vaccines, which have been proven to be effective and safe, varicella has become a disease preventable by specific immunity. This article will review the genomic structure, epidemiological characteristics, and research application progress of varicella vaccine and herpes zoster vaccine of varicella zoster virus to provide reference for primary prevention of the disease.
随着水痘-带状疱疹病毒（VZV）全基因组序列的确定、VZV感染性克隆技术的成功突破以及已被证明安全有效的预防性疫苗的出现，水痘已成为一种可通过特异性免疫预防的疾病。本文将对水痘-带状疱疹病毒的水痘疫苗和带状疱疹疫苗的基因组结构、流行病学特征及研究应用进展进行综述，为该病的一级预防提供参考。
