Department of Dermatology, Pak Emirates Military Hospital, Rawalpindi, Pakistan.
Department of Pharmacology, IIMC, Riphah International University, Rawalpindi, Pakistan.
J Coll Physicians Surg Pak. 2023 Feb;33(2):141-144. doi: 10.29271/jcpsp.2023.02.141.
To test the effectiveness of autoinoculation of a wart in patients with multiple viral warts.
An experimental study.
Department of Dermatology, Pak Emirates Military Hospital (PEMH), Rawalpindi, from February 2021 to February 2022.
Patients above 12 years of age, having more than 5 warts were included. Those getting any other treatment for warts were excluded. The procedure was performed on a total of 70 patients with warts on 3 sites i.e. face/neck, palmoplantar and multiple sites. The outcome was categorised into cleared (no wart), partially cleared (reduced number of warts than baseline), and no response (same or increased number of warts than baseline).
Out of 70 patients, 54 (77.1%) patients showed complete response, 6 (8.6%) showed partial response and 10 (14.3%) showed no response at all. Out of 54 patients who showed complete response, 36 (66.6%) were cleared after only one inoculation, fifteen (27.7%) were cleared after two inoculations, and 3 (5.5%) were cleared after three inoculations. The results were statistically significant with p-value <0.05.
Autoinoculation is a simple and minimally invasive procedure which proved to be very effective against all types of warts, with very promising results against palmoplantar warts.
Viral warts, Multiple viral warts, Autoinoculation, Delayed hypersensitivity, Human papilloma virus (HPV), Palmoplantar warts, Immunity.
测试自体接种疣在多发性病毒性疣患者中的疗效。
实验研究。
巴基斯坦武装部队总医院（PEMH）皮肤科，拉瓦尔品第，2021 年 2 月至 2022 年 2 月。
纳入年龄在 12 岁以上、有 5 个以上疣的患者。排除正在接受其他疣治疗的患者。共有 70 名疣患者在 3 个部位（面部/颈部、手掌/足底和多个部位）进行了该程序。结果分为清除（无疣）、部分清除（比基线减少的疣数）和无反应（与基线相同或增加的疣数）。
70 名患者中，54 名（77.1%）患者出现完全缓解，6 名（8.6%）患者出现部分缓解，10 名（14.3%）患者完全无反应。在 54 名出现完全缓解的患者中，36 名（66.6%）在仅接种一次后即清除，15 名（27.7%）在接种两次后清除，3 名（5.5%）在接种三次后清除。结果具有统计学意义（p 值<0.05）。
自体接种是一种简单且微创的程序，对所有类型的疣均非常有效，对手掌/足底疣的效果非常有前景。
病毒性疣、多发性病毒性疣、自体接种、迟发性超敏反应、人乳头瘤病毒（HPV）、手掌/足底疣、免疫。
