Department of Histopathology, Shifa International Hospital, Islamabad, Pakistan.
Department of Histopathology, Shifa International Hospital, Islamabad.
J Pak Med Assoc. 2023 Feb;73(2):399-401. doi: 10.47391/JPMA.4728.
Gastrointestinal basisdiobolomycosis is a rare fungal infection prevalent in the tropical and subtropical regions. It has variable clinical manifestations that present a challenge for timely diagnosis. Herein, we present a case of gastrointestinal basidiobolomycosis in a 34-year-old male. To the best of our knowledge, it is the first reported case of gastrointestinal basidiobolomycosis from Pakistan. The patient presented with abdominal pain and was first operated for perforated appendix and then for a mesenteric mass based on the findings of CT scan. Histopathologic examination showed broad septate fungal hyphae surrounded by eosinophilic proteinaceous material (Splendore-Hoppeli phenomenon), neutrophils, and histiocytes. Diagnosis of gastrointestinal basidiobolomycosis was established on the basis of this morphology.
胃肠道芽生菌病是一种罕见的真菌感染，主要流行于热带和亚热带地区。它的临床表现多样，给及时诊断带来了挑战。本文报道了一例来自巴基斯坦的 34 岁男性胃肠道芽生菌病患者。据我们所知，这是首例来自巴基斯坦的胃肠道芽生菌病病例。患者表现为腹痛，最初根据 CT 扫描结果行阑尾穿孔手术，后又因肠系膜肿块而行手术治疗。组织病理学检查显示宽间隔的真菌菌丝，周围有嗜酸性蛋白样物质（Splendore-Hoppeli 现象）、中性粒细胞和组织细胞。基于这种形态学表现，诊断为胃肠道芽生菌病。
