Junaid Syeda Tehmina, Muhammad Soima Ali, Ahmed Zeba, Vasandani Rajesh Kumar, Ahmed Jawad
Department of ENT, Head and Neck Surgery, Dow Medical College, Dow University of Health Sciences and Civil Hospital, Karachi, Pakistan.
4th Year MBBS Student, Dow University of Health Sciences, Karachi, Pakistan.
J Pak Med Assoc. 2023 Feb;73(2):412-415. doi: 10.47391/JPMA.5472.
Mammary analogue secretory carcinoma (MASC) is a salivary gland tumour with low-grade potential and specific FTV6 derangement having translocation of chromosomes t (12;15) (p13;q25). It shares a similar morphological as well as an immunohistochemical profile with secretory carcinoma (SC) of the breast making it a diagnostic enigma. In this report, we discuss the case of a 65-year-old male patient, who presented with a complaint of right-sided facial swelling. To rule out the differential, he underwent various diagnostic modalities, including magnetic resonance imaging, fine-needle aspiration and it's the tumour's microscopic and immunohistochemical properties were also reviewed. Parotidectomy along with concurrent chemo-radiotherapy was performed to eradicate the growing mass.
乳腺样分泌性癌（MASC）是一种具有低级别潜能的唾液腺肿瘤，具有特定的FTV6紊乱，伴有染色体t（12；15）（p13；q25）易位。它与乳腺分泌性癌（SC）具有相似的形态学和免疫组化特征，这使其成为一个诊断难题。在本报告中，我们讨论了一例65岁男性患者的病例，该患者主诉右侧面部肿胀。为排除鉴别诊断，他接受了多种诊断方法，包括磁共振成像、细针穿刺，并且还对肿瘤的微观和免疫组化特性进行了评估。进行了腮腺切除术并同时进行放化疗以根除不断生长的肿块。
