用于活细胞中衰老相关 β-半乳糖苷酶传感的近红外荧光纳米探针。
A near-infrared fluorescent nanoprobe for senescence-associated β-galactosidase sensing in living cells.
机构信息
Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.
International Joint Research Center for Photo-responsive Molecules and Materials, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.
出版信息
Chem Commun (Camb). 2023 Mar 7;59(20):2974-2977. doi: 10.1039/d2cc05550c.
A near-infrared fluorescent nanoprobe based on semiconducting polymer nanoparticles (SPNs) for the detection of senescence-associated β-gal (SA-β-gal) is developed. Benefiting from the intrinsic lysosome-locating feature, this probe can be successfully used for the visualization of SA-β-gal in living cells.
开发了一种基于半导体聚合物纳米粒子（SPNs）的近红外荧光纳米探针，用于检测衰老相关β-半乳糖苷酶（SA-β-gal）。得益于内在的溶酶体定位特性，该探针可成功用于活细胞中 SA-β-gal 的可视化。
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