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新生儿接近错失在埃塞俄比亚的流行情况及其决定因素:系统评价和荟萃分析。

Prevalence and determinants of neonatal near miss in Ethiopia: A systematic review and meta-analysis.

机构信息

School of Nursing, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

Department of Midwifery, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.

出版信息

PLoS One. 2023 Feb 21;18(2):e0278741. doi: 10.1371/journal.pone.0278741. eCollection 2023.

DOI:10.1371/journal.pone.0278741
PMID:36809252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9942950/
Abstract

INTRODUCTION

Neonatal near miss is a condition of newborn infant characterized by severe morbidity (near miss), but survived these conditions within the first 27 days of life. It is considered as the first step to design management strategies that can contribute in reducing long term complication and mortality. The aim of this study was to assess prevalence and determinants of neonatal near miss in Ethiopia.

METHODS

The protocol of this systematic review and meta-analysis was registered at the Prospero with a registration number of (PROSPERO 2020: CRD42020206235). International online databases such as PubMed, CINAHL, Google scholar, Global Health, Directory of open Access journal and African Index Medicus were used to search articles. Data extraction was undertaken with Microsoft Excel and STATA11 was used to conduct the Meta-Analysis. Random effect model analysis was considered when there was evidence of heterogeneity between the studies.

RESULTS

The overall pooled prevalence of neonatal near miss was 35.51% (95%CI: 20.32-50.70, I2 = 97.0%, p = 0.000). Primiparity (OR = 2.52, 95%CI: 1.62, 3.42), referral linkage (OR = 3.92, 95%CI: 2.73, 5.12), premature rupture of membrane (OR = 5.05, 95%CI: 2.03, 8.08), Obstructed labor (OR = 4.27, 95%CI: 1.62, 6.91) and maternal medical complications during pregnancy (OR = 7.10, 95%CI: 1.23, 12.98) had shown significant statistical association with neonatal near miss.

CONCLUSION

The prevalence of neonatal near miss in Ethiopia is evidenced to be high. Primiparity, referral linkage, premature rupture of membrane, obstructed labor and maternal medical complications during pregnancy were found to be determinant factors of neonatal near miss.

摘要

引言

新生儿近危象是一种新生儿疾病,其特征为严重的发病率(近危象),但在生命的头 27 天内幸存下来。它被认为是设计管理策略的第一步,可以有助于减少长期并发症和死亡率。本研究的目的是评估新生儿近危象在埃塞俄比亚的流行率和决定因素。

方法

本系统评价和荟萃分析的方案在 Prospero 进行了注册,注册号为(PROSPERO 2020:CRD42020206235)。国际在线数据库,如 PubMed、CINAHL、Google Scholar、全球卫生、开放获取期刊目录和非洲医学索引,用于搜索文章。使用 Microsoft Excel 进行数据提取,使用 STATA11 进行荟萃分析。当研究之间存在异质性证据时,采用随机效应模型分析。

结果

新生儿近危象的总体患病率为 35.51%(95%CI:20.32-50.70,I2 = 97.0%,p = 0.000)。初产妇(OR = 2.52,95%CI:1.62,3.42)、转诊联系(OR = 3.92,95%CI:2.73,5.12)、胎膜早破(OR = 5.05,95%CI:2.03,8.08)、产程受阻(OR = 4.27,95%CI:1.62,6.91)和妊娠期间产妇的医疗并发症(OR = 7.10,95%CI:1.23,12.98)与新生儿近危象有显著的统计学关联。

结论

在埃塞俄比亚,新生儿近危象的流行率很高。初产妇、转诊联系、胎膜早破、产程受阻和妊娠期间产妇的医疗并发症被发现是新生儿近危象的决定因素。

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