Department of Dermatology, Afyonkarahisar Health Sciences University, Afyonkarahisar, 03030, Turkey.
Department of Dermatology, Konya Meram State Hospital, Konya, Turkey.
Arch Dermatol Res. 2023 Aug;315(6):1689-1695. doi: 10.1007/s00403-023-02569-7. Epub 2023 Feb 21.
This study aimed to examine the relationship between acne severity and quality of life, insomnia, and chronotype. This study included 151 patients diagnosed with acne vulgaris, aged 18-30 years. A sociodemographic data form was completed by the clinician, and acne severity was evaluated using the Global Acne Grading System (GAGS). The Visual Analogue Scale (VAS), Acne Quality of Life Scale (AQLS), Hospital Anxiety Depression Scale (HADS), Insomnia Severity Index (ISI), and Morningness-Eveningness Questionnaire (MEQ) were completed by the participants. There was a significant difference between the MEQ scores of the participants who were divided into three groups according to the severity of global acne, as mild, moderate, and severe. In the post hoc analysis, the MEQ scores of the patients with mild acne were determined to be significantly higher than the scores of the patients with moderate and severe acne. A statistically significant negative correlation was observed between the GAGS scores and the MEQ scores. In addition, a statistically significant positive correlation was found between the participants' ISI scores and AQLS scores. Considering the variables related to chronotype and sleep in the treatment planning for patients with acne vulgaris may be appropriate within the scope of integrative treatment.
本研究旨在探讨痤疮严重程度与生活质量、失眠和昼夜节律之间的关系。本研究纳入了 151 名年龄在 18-30 岁之间的寻常痤疮患者。临床医生填写了一份社会人口统计学数据表格,使用全球痤疮分级系统(GAGS)评估痤疮严重程度。参与者完成了视觉模拟量表(VAS)、痤疮生活质量量表(AQLS)、医院焦虑抑郁量表(HADS)、失眠严重程度指数(ISI)和 Morningness-Eveningness Questionnaire(MEQ)。根据全球痤疮严重程度将参与者分为轻度、中度和重度三组,三组的 MEQ 评分存在显著差异。在事后分析中,轻度痤疮患者的 MEQ 评分明显高于中度和重度痤疮患者。GAGS 评分与 MEQ 评分呈显著负相关。此外,参与者的 ISI 评分与 AQLS 评分呈显著正相关。在寻常痤疮患者的综合治疗范围内,考虑与昼夜节律和睡眠相关的变量可能是适当的。