Koźlik Maciej, Harpula Jan, Chuchra Piotr J, Nowak Magdalena, Wojakowski Wojciech, Gąsior Paweł
Division of Cardiology and Structural Heart Disease, Medical University of Silesia, 40-635 Katowice, Poland.
Students' Scientific Society, Department of Cardiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-635 Katowice, Poland.
Biomimetics (Basel). 2023 Feb 9;8(1):72. doi: 10.3390/biomimetics8010072.
Drug-eluting stents (DES) demonstrated superior efficacy when compared to bare metal stents and plain-old balloon angioplasty and are nowadays used in almost all percutaneous revascularization procedures. The design of the stent platforms is constantly improving to maximize its efficacy and safety. Constant development of DES includes adoption of new materials used for scaffold production, new design types, improved overexpansion abilities, new polymers coating and, finally, improved antiproliferative agents. Especially nowadays, with the immense number of available DES platforms, it is crucial to understand how different aspects of stents impact the effect of their implantation, as subtle differences between various stent platforms could impact the most important issue-clinical outcomes. This review discusses the current status of coronary stents and the impact of stent material, strut design and coating techniques on cardiovascular outcomes.
与裸金属支架和普通球囊血管成形术相比,药物洗脱支架(DES)显示出更高的疗效,如今几乎用于所有经皮血管重建手术。支架平台的设计不断改进,以最大限度地提高其疗效和安全性。DES的不断发展包括采用用于支架生产的新材料、新的设计类型、改进的过度扩张能力、新的聚合物涂层,以及最终改进的抗增殖剂。特别是如今,有大量可用的DES平台,了解支架的不同方面如何影响其植入效果至关重要,因为各种支架平台之间的细微差异可能会影响最重要的问题——临床结果。本综述讨论了冠状动脉支架的现状以及支架材料、支柱设计和涂层技术对心血管结局的影响。