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金凤花氧气原则：不多不少。

The Goldilocks Oxygen Principle: not too little and not too much.

作者信息

Flanigan Will R, Jain Isha H

机构信息

Gladstone Institutes, San Francisco, CA, USA.

UCSF-UC Berkeley Joint PhD Program in Bioengineering, Berkeley, CA, USA.

出版信息

Nat Cardiovasc Res. 2022 Dec;1(12):1101-1103. doi: 10.1038/s44161-022-00178-7. Epub 2022 Dec 12.

DOI:10.1038/s44161-022-00178-7
PMID:36816751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9937547/
Abstract

Nature has evolved creative ways to maintain oxygen homeostasis, but what happens when these adaptations are insufficient? Here we discuss biochemical failure points across the oxygen spectrum from 'too little' to 'too much' oxygen and their potential contributions to cardiovascular disease.

摘要

大自然已经进化出了维持氧稳态的创新方法，但是当这些适应性机制不足时会发生什么呢？在这里，我们讨论了从“氧含量过少”到“氧含量过多”整个氧范围内的生化故障点及其对心血管疾病的潜在影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be98/9937547/2994eeb10c46/nihms-1867291-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be98/9937547/2994eeb10c46/nihms-1867291-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be98/9937547/2994eeb10c46/nihms-1867291-f0001.jpg

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