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成人幼年性息肉。

JUVENILE POLYP IN ADULTS.

机构信息

University of Novi Sad, Faculty of Medicine, Department of Histology and Embryology, Novi Sad, Serbia.

Oncology Institute of Vojvodina, Sremska Kamenica, Serbia.

出版信息

Acta Clin Croat. 2022 Aug;61(2):354-358. doi: 10.20471/acc.2022.61.02.23.

DOI:10.20471/acc.2022.61.02.23
PMID:36818922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9934046/
Abstract

Colorectal juvenile polyp as a pathologic entity was first described by Verse. These non-neoplastic lesions are most commonly found in children and infants, while in older children after the age of 14 and adults are a rare phenomenon. A 75-year-old female underwent colonoscopy. There was a pedunculated polyp in the transverse colon. Complete endoscopic electroresection of this polyp was performed and the polyp was sent for histopathologic analysis. Macroscopically, the polyp was described as a fragment of irregular round shape, size of about 2.5x2x1 cm, with fine-grained, reddish surface, showing dark red color on serial sections. Histologic examination of the polyp showed some irregularly distributed glands, some of which were cystically dilated. All glandular formations were coated with normal intestinal epithelium. The surface of the polyp was partially eroded and replaced by non-specific cellular granulation tissue. There were some signs of hemorrhagic infarction in the stroma of the polyp. Histopathologic examination indicated that histopathologic characteristics of this polyp corresponded to juvenile polyp. Juvenile polyps are very rarely found in adults. Therefore, we describe a case of this patient in her eighties with juvenile polyp localized in the transverse colon.

摘要

结肠幼年性息肉作为一种病理实体,最早由 Verse 描述。这些非肿瘤性病变最常见于儿童和婴儿,而在 14 岁以上的儿童和成人中则是罕见现象。一名 75 岁女性接受了结肠镜检查。横结肠有一个带蒂息肉。对该息肉进行了完全的内镜电切除,并将息肉送去进行组织病理学分析。大体上,息肉描述为不规则圆形的碎片,大小约为 2.5x2x1cm,表面有细颗粒状、红色,在连续切片上显示暗红色。息肉的组织学检查显示一些不规则分布的腺体,其中一些呈囊状扩张。所有腺体形成物均被正常肠上皮覆盖。息肉表面部分被侵蚀,被非特异性细胞肉芽组织取代。息肉的基质中有一些出血性梗死的迹象。组织病理学检查表明,该息肉的组织病理学特征与幼年性息肉相对应。幼年性息肉在成人中非常罕见。因此,我们描述了一例 80 多岁的患者,其横结肠中存在幼年性息肉。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d7/9934046/daeeb426f458/acc-61-354-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d7/9934046/1b140cee13d0/acc-61-354-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d7/9934046/be97964548cf/acc-61-354-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d7/9934046/daeeb426f458/acc-61-354-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d7/9934046/1b140cee13d0/acc-61-354-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d7/9934046/be97964548cf/acc-61-354-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d7/9934046/daeeb426f458/acc-61-354-f3.jpg

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Hamartomatous polyps - a clinical and molecular genetic study.错构瘤性息肉——一项临床与分子遗传学研究
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Juvenile Polyps in Denmark From 1995 to 2014.1995年至2014年丹麦的幼年息肉
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