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体外冲击波疗法治疗腕管综合征的临床和电生理疗效:一项安慰剂对照、双盲临床试验。

Clinical and electrophysiological efficacy of extracorporeal shock-wave therapy in carpal tunnel syndrome: a placebo-controlled, double-blind clinical trial.

机构信息

Sağlık Bilimleri Üniversitesi, İstanbul Kanuni Sultan Suleyman Training and Research Hospital, Department of Physical Medicine and Rehabilitation - Istanbul, Turkey.

Sağlık Bilimleri Üniversitesi, İstanbul Kanuni Sultan Suleyman Training and Research Hospital, Department of Neurology - Istanbul, Turkey.

出版信息

Rev Assoc Med Bras (1992). 2023 Feb 17;69(1):124-130. doi: 10.1590/1806-9282.20220943. eCollection 2023.

DOI:10.1590/1806-9282.20220943
PMID:36820719
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9937620/
Abstract

OBJECTIVE

The aim of this study was to evaluate the efficacy of radial extracorporeal shock wave therapy on pain, functionality, and electrophysiological measurements in carpal tunnel syndrome.

METHODS

Between June 2021 and January 2022, a total of 66 wrists in 45 participants with mild-to-moderate carpal tunnel syndrome were included in this double-blind, prospective, randomized, placebo-controlled study. Patients were randomized into two groups, namely, the radial extracorporeal shock wave therapy (group 1, n=33) and the sham radial extracorporeal shock wave therapy (group 2, n=33). Night splints and tendon nerve gliding exercises were given to all participants. The participants were evaluated at baseline and the first month after treatment. Participants were evaluated using a visual analog scale, the Boston Carpal Tunnel Questionnaire, Leeds Neuropathic Symptom and Symptom Assessment, and electrophysiological examinations.

RESULTS

A total of 37 participants (a total of 55 wrists, radial extracorporeal shock wave therapy n=27, and sham radial extracorporeal shock wave therapy n=28) completed the study. After the intervention, there was a significant decrease in visual analog scale values (p<0.001) and a significant increase in Boston Carpal Tunnel Questionnaire scores (p<0.001) and Leeds Neuropathic Symptom and Symptom Assessment scores (p<0.001). In electrophysiological measurements, there was a significant decrease in median nerve sensory (p=0.002) and motor (p=0.003) distal latency, and a significant increase in median nerve sensory conduction velocity (p=0.026) was found in the radial extracorporeal shock wave therapy group.

CONCLUSION

This study shows that radial extracorporeal shock wave therapy has positive effects on pain, functionality, and electrophysiological measurements for mild-to-moderate carpal tunnel syndrome 1 month after application.

摘要

目的

本研究旨在评估桡动脉体外冲击波疗法对腕管综合征疼痛、功能和电生理测量的疗效。

方法

2021 年 6 月至 2022 年 1 月,共纳入 45 名参与者的 66 只手腕,均为轻中度腕管综合征患者,进行了这项双盲、前瞻性、随机、安慰剂对照研究。将患者随机分为两组,即桡动脉体外冲击波治疗组(第 1 组,n=33)和假桡动脉体外冲击波治疗组(第 2 组,n=33)。所有参与者均给予夜间夹板和肌腱神经滑动练习。在基线和治疗后 1 个月对参与者进行评估。参与者使用视觉模拟评分法、波士顿腕管问卷、利兹神经症状和症状评估以及电生理检查进行评估。

结果

共有 37 名参与者(共 55 只手腕,桡动脉体外冲击波治疗组 n=27,假桡动脉体外冲击波治疗组 n=28)完成了研究。干预后,视觉模拟评分值显著下降(p<0.001),波士顿腕管问卷评分(p<0.001)和利兹神经症状和症状评估评分(p<0.001)显著增加。在电生理测量中,桡动脉体外冲击波治疗组正中神经感觉(p=0.002)和运动(p=0.003)远端潜伏期显著降低,正中神经感觉传导速度(p=0.026)显著增加。

结论

本研究表明,桡动脉体外冲击波疗法在应用后 1 个月对轻中度腕管综合征的疼痛、功能和电生理测量具有积极影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9eb4/9937620/208451951be2/1806-9282-ramb-69-01-0124-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9eb4/9937620/208451951be2/1806-9282-ramb-69-01-0124-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9eb4/9937620/208451951be2/1806-9282-ramb-69-01-0124-gf01.jpg

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