2020-2021 年巴西新生儿的 COVID-19 严重急性呼吸道综合征。
COVID-19 severe acute respiratory syndrome in Brazilian newborns in 2020-2021.
机构信息
Universidade Federal do Maranhão, School of Medicine - São Luís (MA), Brazil.
Universidade Federal do Maranhão, Graduate Program in Collective Health - São Luís (MA), Brazil.
出版信息
Rev Bras Epidemiol. 2023 Feb 20;26:e230012. doi: 10.1590/1980-549720230012. eCollection 2023.
OBJECTIVE
To describe the clinical characteristics of cases of COVID-19 severe acute respiratory syndrome (SARS) in Brazilian newborns (NBs) in 2020 and 2021, recorded in the Influenza Epidemiological Surveillance Information System (Sistema de Informação da Vigilância Epidemiológica da Gripe - SIVEP-Gripe).
METHODS
The variables analyzed were gender, race/skin color, hospitalization, intensive care unit (ICU) admission, use of ventilatory support, signs and symptoms (fever, cough, O2 saturation<95%, dyspnea, respiratory distress, diarrhea, and vomiting), progress (death or cure), risk factors/comorbidities. Categorical variables were expressed as absolute and relative frequencies.
RESULTS
We found 1,649 records of COVID-19 SARS in NBs, with a predominance of multiracial babies in both years. The most frequent symptoms in 2020 and 2021 were, respectively: respiratory distress (67.0 and 69.7%), fever (46.3 and 46.2%), and cough (37.0 and 46.3%). In 2020, 30.5% of patients received invasive ventilatory support; in 2021, this number was 41.6%. In addition, more than 55% of cases required ICU admission, and over 16% died.
CONCLUSION
We emphasize the high proportion of cases that required intensive care and progressed to death.
目的
描述 2020 年和 2021 年巴西新生儿（NB）中 COVID-19 严重急性呼吸综合征（SARS）病例的临床特征，这些病例记录在流感流行病学监测信息系统（Sistema de Informação da Vigilância Epidemiológica da Gripe - SIVEP-Gripe）中。
方法
分析的变量包括性别、种族/肤色、住院、重症监护病房（ICU）入院、使用呼吸机支持、体征和症状（发热、咳嗽、O2 饱和度<95%、呼吸困难、呼吸窘迫、腹泻和呕吐）、进展（死亡或治愈）、危险因素/合并症。分类变量表示为绝对和相对频率。
结果
我们发现 1649 例 COVID-19 SARS 在 NB 中的记录，在这两年中，多种族婴儿均占多数。2020 年和 2021 年最常见的症状分别为：呼吸窘迫（67.0%和 69.7%）、发热（46.3%和 46.2%）和咳嗽（37.0%和 46.3%）。2020 年，30.5%的患者接受了有创性呼吸机支持；2021 年，这一数字为 41.6%。此外，超过 55%的病例需要入住 ICU，超过 16%的病例死亡。
结论
我们强调需要重症监护和进展为死亡的病例比例很高。
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