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老年人便秘的全球患病率:系统评价和荟萃分析。

Global prevalence of constipation in older adults: a systematic review and meta-analysis.

机构信息

Department of Biostatistics, School of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

Wien Klin Wochenschr. 2023 Aug;135(15-16):389-398. doi: 10.1007/s00508-023-02156-w. Epub 2023 Feb 24.

Abstract

BACKGROUND AND OBJECTIVE

Constipation is one of the most common functional disorders of the gastrointestinal tract in older adults. To date, no systematic review or previous meta-analysis has estimated the global prevalence of constipation in older adults. The prevalence of this disorder has been reported differently in different studies; therefore, this study aims to systematically review the publications and to perform a meta-analysis of the prevalence of constipation in older adults.

METHODS

The electronic databases PubMed, Google Scholar, Scopus, Web of Science, and ScienceDirect were systematically searched for studies reporting the prevalence of constipation in older adults up to February 2022. To perform the analysis, the random effects model was used, and heterogeneity was assessed by Cochran's Q test and expressed as I.

RESULTS

Out of 5341 evaluated publications, 36 met the eligibility criteria. These studies included 58,405 older adults aged 60-93 years. The overall prevalence of constipation in older adults was 18.9% (95% confidence interval [95% CI]: 14.7-23.9%). The prevalence of constipation in older adults according to Rome II criteria was 16.2% (95% CI: 6.8-33.7), based on Rome III criteria was 19.2% (95% CI: 12.6-28.1), and based on Rome IV criteria was 10.3% (95% CI: 5.8-17.7). The highest prevalence of constipation was found in older adults in Africa at 32.3% (95% CI: 21.5-45.4), and the lowest in Asia at 13.6% (95% CI: 9.1-19.9). Concerning diagnostic tools, the highest prevalence of constipation was found if a self-reporting tool was applied with a value of 19.7% (95% CI: 15.8-24.3).

CONCLUSION

The results suggest that health policymakers should pay more attention to the prevention of constipation in older adults, including raising public awareness to the importance of nutrition and diet and physical activity in older adults.

摘要

背景与目的

便秘是老年人胃肠道最常见的功能障碍之一。迄今为止,尚无系统评价或既往荟萃分析估计老年人便秘的全球患病率。不同研究报道的该疾病患病率存在差异;因此,本研究旨在对相关文献进行系统回顾,并对老年人便秘的患病率进行荟萃分析。

方法

系统检索了截至 2022 年 2 月PubMed、Google Scholar、Scopus、Web of Science 和 ScienceDirect 电子数据库中报告老年人便秘患病率的研究。采用随机效应模型进行分析,采用 Cochran's Q 检验评估异质性,并以 I 表示。

结果

在评估的 5341 篇文献中,有 36 篇符合纳入标准。这些研究纳入了 58405 名 60-93 岁的老年人。老年人便秘的总体患病率为 18.9%(95%置信区间[95%CI]:14.7-23.9%)。根据罗马 II 标准,老年人便秘的患病率为 16.2%(95%CI:6.8-33.7%),根据罗马 III 标准为 19.2%(95%CI:12.6-28.1%),根据罗马 IV 标准为 10.3%(95%CI:5.8-17.7%)。在非洲,老年人便秘的患病率最高,为 32.3%(95%CI:21.5-45.4%),在亚洲最低,为 13.6%(95%CI:9.1-19.9%)。关于诊断工具,应用自我报告工具时,便秘的患病率最高,为 19.7%(95%CI:15.8-24.3%)。

结论

结果表明,卫生政策制定者应更加关注老年人便秘的预防,包括提高公众对老年人营养、饮食和身体活动重要性的认识。

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