Schneidewind Laila, Kiss Bernhard, Stangl Fabian P, Tandogdu Zafer, Wagenlehner Florian M E, Johansen Truls E Bjerklund, Köves Béla, Medina-Polo Jose, Tapia Ana Maria, Kranz Jennifer
Department of Urology, University Medical Center Rostock, 18057 Rostock, Germany.
Department of Urology, University Hospital of Bern, 3010 Bern, Switzerland.
Antibiotics (Basel). 2023 Jan 18;12(2):197. doi: 10.3390/antibiotics12020197.
Fournier's gangrene (FG) is a life-threatening, necrotizing infection. Due to the rareness of the disease, it is challenging to plan robust prospective studies. This study aims to describe current practice patterns of FG in Europe and identify implications for planning a prospective FG registry.
Online non-validated 17-items survey among urologists treating FG in in European hospitals. Questionnaires were analyzed with LimeSurvey (LimeSurvey GmbH Hamburg, Germany).
229 responses from ten different European countries were submitted, and 117 (51.1%) urologists completed the questionnaire. The departments treat a mean of 4.2 (SD 3.11) patients per year. The urology department mostly takes the lead in treating FG patients ( = 113; 96.6%). The practice in FG is very heterogenic and mostly case-based all over Europe, e.g., vacuum-assisted wound closure (VAC) is mostly used ( = 50; 42.7%) as adjunct wound. The biggest challenges in FG are the short time to diagnosis and treatment, standardization and establishment of guidelines, and disease awareness. Additionally, participants stated that an international registry is an outstanding initiative, and predictive models are needed.
There is no standard of care in the diagnosis, treatment, and long-term care of FG all over Europe. Further research could be conducted with a prospective registry.
福尼尔坏疽（FG）是一种危及生命的坏死性感染。由于该疾病罕见，开展强有力的前瞻性研究具有挑战性。本研究旨在描述欧洲FG的当前实践模式，并确定对规划前瞻性FG登记处的影响。
对欧洲医院治疗FG的泌尿科医生进行一项17项的在线非验证性调查。问卷采用LimeSurvey（德国汉堡LimeSurvey有限公司）进行分析。
共收到来自10个不同欧洲国家的229份回复，117名（51.1%）泌尿科医生完成了问卷。各科室每年平均治疗4.2名（标准差3.11）患者。泌尿外科大多牵头治疗FG患者（n = 113；96.6%）。FG的治疗方法在欧洲各地差异很大，且大多基于病例，例如，负压伤口治疗（VAC）大多被用作辅助伤口治疗（n = 50；42.7%）。FG面临的最大挑战是诊断和治疗时间短、指南的标准化和制定以及疾病认知度。此外，参与者表示国际登记处是一项杰出的举措，并且需要预测模型。
在欧洲，FG的诊断、治疗和长期护理没有统一的标准治疗方案。可以通过前瞻性登记处开展进一步研究。
