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基于二维(2D)的杂化材料的光抗菌活性:控制细菌感染的有效治疗策略

Photo-Antibacterial Activity of Two-Dimensional (2D)-Based Hybrid Materials: Effective Treatment Strategy for Controlling Bacterial Infection.

作者信息

Talreja Neetu, Chauhan Divya, Ashfaq Mohammad

机构信息

Department of Science, Faculty of Science and Technology, Alliance University, Anekal, Bengaluru 562106, India.

Department of Drinking Water and Sanitation, Ministry of Jal Shakti, New Delhi 110003, India.

出版信息

Antibiotics (Basel). 2023 Feb 16;12(2):398. doi: 10.3390/antibiotics12020398.

DOI:10.3390/antibiotics12020398
PMID:36830308
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9952232/
Abstract

Bacterial contamination in water bodies is a severe scourge that affects human health and causes mortality and morbidity. Researchers continue to develop next-generation materials for controlling bacterial infections from water. Photo-antibacterial activity continues to gain the interest of researchers due to its adequate, rapid, and antibiotic-free process. Photo-antibacterial materials do not have any side effects and have a minimal chance of developing bacterial resistance due to their rapid efficacy. Photocatalytic two-dimensional nanomaterials (2D-NMs) have great potential for the control of bacterial infection due to their exceptional properties, such as high surface area, tunable band gap, specific structure, and tunable surface functional groups. Moreover, the optical and electric properties of 2D-NMs might be tuned by creating heterojunctions or by the doping of metals/carbon/polymers, subsequently enhancing their photo-antibacterial ability. This review article focuses on the synthesis of 2D-NM-based hybrid materials, the effect of dopants in 2D-NMs, and their photo-antibacterial application. We also discuss how we could improve photo-antibacterials by using different strategies and the role of artificial intelligence (AI) in the photocatalyst and in the degradation of pollutants. Finally, we discuss was of improving the photo-antibacterial activity of 2D-NMs, the toxicity mechanism, and their challenges.

摘要

水体中的细菌污染是一种严重的灾祸,会影响人类健康并导致死亡和发病。研究人员不断研发用于控制水体细菌感染的下一代材料。光抗菌活性因其充分、快速且无抗生素的过程而持续引起研究人员的兴趣。光抗菌材料没有任何副作用,并且由于其快速起效,产生细菌耐药性的可能性极小。光催化二维纳米材料(2D-NMs)因其具有诸如高表面积、可调节带隙、特定结构和可调节表面官能团等特殊性质,在控制细菌感染方面具有巨大潜力。此外,二维纳米材料的光学和电学性质可以通过创建异质结或通过金属/碳/聚合物掺杂来调节,从而增强其光抗菌能力。这篇综述文章聚焦于基于二维纳米材料的杂化材料的合成、二维纳米材料中掺杂剂的作用及其光抗菌应用。我们还讨论了如何通过使用不同策略来改进光抗菌剂,以及人工智能(AI)在光催化剂和污染物降解中的作用。最后,我们讨论了提高二维纳米材料光抗菌活性的方法、毒性机制及其面临的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/6b424f1b5b74/antibiotics-12-00398-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/eddf0ad22d4b/antibiotics-12-00398-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/aa4dab628588/antibiotics-12-00398-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/b30ed43ee50d/antibiotics-12-00398-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/0374a69af10b/antibiotics-12-00398-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/99d4d96bcaf9/antibiotics-12-00398-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/fba99a7884b8/antibiotics-12-00398-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/1a664f8febd1/antibiotics-12-00398-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/6b424f1b5b74/antibiotics-12-00398-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/eddf0ad22d4b/antibiotics-12-00398-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/aa4dab628588/antibiotics-12-00398-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/b30ed43ee50d/antibiotics-12-00398-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/0374a69af10b/antibiotics-12-00398-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/99d4d96bcaf9/antibiotics-12-00398-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/fba99a7884b8/antibiotics-12-00398-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/1a664f8febd1/antibiotics-12-00398-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c3/9952232/6b424f1b5b74/antibiotics-12-00398-g008.jpg

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