人体糖原的天然丰度13C核磁共振谱。
Natural abundance 13C NMR spectrum of glycogen in humans.
作者信息
Jue T, Lohman J A, Ordidge R J, Shulman R G
机构信息
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06511.
出版信息
Magn Reson Med. 1987 Oct;5(4):377-9. doi: 10.1002/mrm.1910050410.
PMID:3683168
Abstract
In vivo NMR has focused on using 31P and 1H to study metabolism in humans. Comparable 13C NMR studies have not been undertaken, presumably, because of its insensitivity. We report herein that the natural abundance 13C signal from C1 glycogen is observable. The ability to observe the signal opens new opportunities to noninvasively study glycogen metabolism in man.
摘要
体内核磁共振已聚焦于利用磷-31和氢-1来研究人体新陈代谢。据推测，尚未开展类似的碳-13核磁共振研究是因为其灵敏度不够。我们在此报告，来自糖原C1的天然丰度碳-13信号是可观测到的。观测该信号的能力为无创研究人体糖原代谢带来了新机遇。
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