Træningscenter Brøndby, Horsedammen 36A, 2605 Brøndby, Denmark.
Department of Health Sciences, Faculty of Medicine, Lund University, P.O. Box 157, 22100 Lund, Sweden.
Int J Environ Res Public Health. 2023 Feb 10;20(4):3107. doi: 10.3390/ijerph20043107.
Although hip fractures are common and severe, there is insufficient evidence concerning which type of rehabilitation is most beneficial. The primary aim of this three-armed pilot study was to investigate any difference in outcome after hip fractures between and within groups in terms of balance, everyday activities, and health-related quality of life (HRQoL) following different home rehabilitation interventions. Further aims were to study feasibility and to suggest, if necessary, adjustments to the protocol for a future full randomized controlled trial (RCT). In total, 32 persons were included in this study. The intervention groups underwent the HIFE program with or without an inertial measurement unit, while the control group underwent standard rehabilitation. Within- and between-groups differences in outcomes and feasibility outcomes in terms of recruitment and retention rates were analyzed, and the ability to collect primary and secondary outcomes was assessed. Balance, measured as postural sway, showed no significant improvement in any group. All three groups improved in functional balance ( = 0.011-0.028), activity of daily living ( = 0.012-0.027), and in HRQoL ( = 0.017-0.028). There were no other significant changes within or between the groups. The recruitment rate was 46%, the retention rate was 75%, and the ability to collect outcome measures was 80% at baseline and 64% at follow-up. Based on the results, it is possible to, after adjusting the protocol, conduct a full RCT.
尽管髋部骨折很常见且很严重,但关于哪种康复方式最有益,证据还不够充分。这项三臂试验研究的主要目的是调查在不同家庭康复干预后,髋部骨折患者在平衡、日常活动和健康相关生活质量(HRQoL)方面的结果是否存在组间和组内差异。进一步的目的是研究可行性,并在必要时为未来的全随机对照试验(RCT)调整方案。共有 32 名患者参与了这项研究。干预组接受 HIFE 计划,或同时使用惯性测量单元,而对照组则接受标准康复。分析了组内和组间差异以及在招募和保留率方面的可行性结果,并评估了收集主要和次要结果的能力。平衡方面,姿势摆动没有显示出任何组的显著改善。所有三组在功能性平衡(=0.011-0.028)、日常生活活动(=0.012-0.027)和 HRQoL(=0.017-0.028)方面都有所改善。组内或组间没有其他显著变化。招募率为 46%,保留率为 75%,基线时收集结局测量的能力为 80%,随访时为 64%。基于这些结果,在调整方案后,可以进行全面的 RCT。