School of Public health Sciences, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
Whiting School of Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Int J Environ Res Public Health. 2023 Feb 13;20(4):3262. doi: 10.3390/ijerph20043262.
The COVID-19 pandemic is an epidemiological and psychological crisis; what it does to the body is quite well known by now, and more research is underway, but the syndemic impact of COVID-19 and mental health on underlying chronic illnesses among the general population is not completely understood.
We carried out a literature review to identify the potential impact of COVID-19 and related mental health issues on underlying comorbidities that could affect the overall health of the population.
Many available studies have highlighted the impact of COVID-19 on mental health only, but how complex their interaction is in patients with comorbidities and COVID-19, the absolute risks, and how they connect with the interrelated risks in the general population, remain unknown. The COVID-19 pandemic can be recognized as a syndemic due to; synergistic interactions among different diseases and other health conditions, increasing overall illness burden, emergence, spread, and interactions between infectious zoonotic diseases leading to new infectious zoonotic diseases; this is together with social and health interactions leading to increased risks in vulnerable populations and exacerbating clustering of multiple diseases.
There is a need to develop evidence to support appropriate and effective interventions for the overall improvement of health and psychosocial wellbeing of at-risk populations during this pandemic. The syndemic framework is an important framework that can be used to investigate and examine the potential benefits and impact of codesigning COVID-19/non-communicable diseases (NCDs)/mental health programming services which can tackle these epidemics concurrently.
COVID-19 大流行是一场流行病学和心理危机；现在人们已经相当了解它对身体的影响，并且正在进行更多的研究，但 COVID-19 和心理健康对普通人群中潜在慢性疾病的综合影响尚未完全了解。
我们进行了文献综述，以确定 COVID-19 和相关心理健康问题对潜在合并症的潜在影响，这些合并症可能会影响人群的整体健康。
许多现有研究仅强调了 COVID-19 对心理健康的影响，但它们在合并症和 COVID-19 患者中的相互作用有多复杂、绝对风险以及它们如何与普通人群中的相关风险相关联，这些仍不清楚。COVID-19 大流行可以被视为一种综合病，因为不同疾病和其他健康状况之间存在协同相互作用，增加了整体疾病负担，传染病动物源性疾病的出现、传播和相互作用导致新的传染病动物源性疾病；再加上社会和健康相互作用，导致弱势群体的风险增加，并使多种疾病的聚集加剧。
需要制定证据以支持在这场大流行期间为高危人群提供整体改善健康和心理社会福祉的适当和有效干预措施。综合病框架是一个重要的框架，可以用于调查和研究共同设计 COVID-19/非传染性疾病（NCD）/心理健康规划服务的潜在好处和影响，这些服务可以同时应对这些流行病。
