• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

利用优化和可解释的机器学习提高重症监护病房早期再入院预测

Improving Intensive Care Unit Early Readmission Prediction Using Optimized and Explainable Machine Learning.

机构信息

Galicia Sur Health Research Institute (IIS Galicia Sur), Álvaro Cunqueiro Hospital, 36310 Vigo, Spain.

Department of Electronic Technology, University of Vigo, 36310 Vigo, Spain.

出版信息

Int J Environ Res Public Health. 2023 Feb 16;20(4):3455. doi: 10.3390/ijerph20043455.

DOI:10.3390/ijerph20043455
PMID:36834150
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9960143/
Abstract

It is of great interest to develop and introduce new techniques to automatically and efficiently analyze the enormous amount of data generated in today's hospitals, using state-of-the-art artificial intelligence methods. Patients readmitted to the ICU in the same hospital stay have a higher risk of mortality, morbidity, longer length of stay, and increased cost. The methodology proposed to predict ICU readmission could improve the patients' care. The objective of this work is to explore and evaluate the potential improvement of existing models for predicting early ICU patient readmission by using optimized artificial intelligence algorithms and explainability techniques. In this work, XGBoost is used as a predictor model, combined with Bayesian techniques to optimize it. The results obtained predicted early ICU readmission (AUROC of 0.92 ± 0.03) improves state-of-the-art consulted works (whose AUROC oscillate between 0.66 and 0.78). Moreover, we explain the internal functioning of the model by using Shapley Additive Explanation-based techniques, allowing us to understand the model internal performance and to obtain useful information, as patient-specific information, the thresholds from which a feature begins to be critical for a certain group of patients, and the feature importance ranking.

摘要

开发并引入新技术,使用最先进的人工智能方法,自动有效地分析当今医院产生的大量数据,这是非常有意义的。在同一住院期间再次入住 ICU 的患者的死亡率、发病率更高,住院时间更长,成本增加。提出的预测 ICU 再入院的方法可以改善患者的护理。本工作的目的是探索和评估通过使用优化的人工智能算法和可解释性技术,对现有预测早期 ICU 患者再入院的模型进行潜在改进。在本工作中,使用 XGBoost 作为预测模型,并结合贝叶斯技术对其进行优化。所获得的结果预测了早期 ICU 再入院(AUROC 为 0.92 ± 0.03),优于已咨询的最先进技术(其 AUROC 在 0.66 到 0.78 之间波动)。此外,我们使用 Shapley Additive Explanation-based 技术来解释模型的内部功能,使我们能够了解模型的内部性能并获得有用的信息,例如患者特定信息、特征开始对某些患者群体变得关键的阈值,以及特征重要性排序。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/8f051c250edb/ijerph-20-03455-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/22a52c4d4444/ijerph-20-03455-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/7a383cd9ebe0/ijerph-20-03455-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/7b04e97ed1a8/ijerph-20-03455-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/3ecaf11f60c1/ijerph-20-03455-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/ae50493fd2f4/ijerph-20-03455-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/30ba1bb16873/ijerph-20-03455-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/dc6386202942/ijerph-20-03455-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/8f051c250edb/ijerph-20-03455-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/22a52c4d4444/ijerph-20-03455-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/7a383cd9ebe0/ijerph-20-03455-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/7b04e97ed1a8/ijerph-20-03455-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/3ecaf11f60c1/ijerph-20-03455-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/ae50493fd2f4/ijerph-20-03455-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/30ba1bb16873/ijerph-20-03455-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/dc6386202942/ijerph-20-03455-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d57/9960143/8f051c250edb/ijerph-20-03455-g008.jpg

相似文献

1
Improving Intensive Care Unit Early Readmission Prediction Using Optimized and Explainable Machine Learning.利用优化和可解释的机器学习提高重症监护病房早期再入院预测
Int J Environ Res Public Health. 2023 Feb 16;20(4):3455. doi: 10.3390/ijerph20043455.
2
[Prediction of intensive care unit readmission for critically ill patients based on ensemble learning].基于集成学习的危重症患者重症监护病房再入院预测
Beijing Da Xue Xue Bao Yi Xue Ban. 2021 Jun 18;53(3):566-572. doi: 10.19723/j.issn.1671-167X.2021.03.021.
3
Two-Step Approach for Occupancy Estimation in Intensive Care Units Based on Bayesian Optimization Techniques.基于贝叶斯优化技术的重症监护病房入住率两步估计法。
Sensors (Basel). 2023 Jan 19;23(3):1162. doi: 10.3390/s23031162.
4
An explainable machine learning algorithm for risk factor analysis of in-hospital mortality in sepsis survivors with ICU readmission.一种用于分析脓毒症幸存者再次入住重症监护病房时院内死亡风险因素的可解释机器学习算法。
Comput Methods Programs Biomed. 2021 Jun;204:106040. doi: 10.1016/j.cmpb.2021.106040. Epub 2021 Mar 7.
5
Explainable Machine-Learning Model for Prediction of In-Hospital Mortality in Septic Patients Requiring Intensive Care Unit Readmission.用于预测需要再次入住重症监护病房的脓毒症患者院内死亡率的可解释机器学习模型
Infect Dis Ther. 2022 Aug;11(4):1695-1713. doi: 10.1007/s40121-022-00671-3. Epub 2022 Jul 14.
6
An explainable knowledge distillation method with XGBoost for ICU mortality prediction.一种基于XGBoost的用于重症监护病房死亡率预测的可解释知识蒸馏方法。
Comput Biol Med. 2023 Jan;152:106466. doi: 10.1016/j.compbiomed.2022.106466. Epub 2022 Dec 21.
7
Analysis and prediction of unplanned intensive care unit readmission using recurrent neural networks with long short-term memory.基于长短时记忆递归神经网络的非计划性重症监护病房再入院分析与预测。
PLoS One. 2019 Jul 8;14(7):e0218942. doi: 10.1371/journal.pone.0218942. eCollection 2019.
8
Prediction of early unplanned intensive care unit readmission in a UK tertiary care hospital: a cross-sectional machine learning approach.英国一家三级护理医院早期非计划重症监护病房再入院的预测:一种横断面机器学习方法。
BMJ Open. 2017 Sep 15;7(9):e017199. doi: 10.1136/bmjopen-2017-017199.
9
Using Explainable Machine Learning to Improve Intensive Care Unit Alarm Systems.使用可解释机器学习来改进重症监护病房警报系统。
Sensors (Basel). 2021 Oct 27;21(21):7125. doi: 10.3390/s21217125.
10
Predicting Mortality in Intensive Care Unit Patients With Heart Failure Using an Interpretable Machine Learning Model: Retrospective Cohort Study.利用可解释机器学习模型预测重症监护病房心力衰竭患者的死亡率:回顾性队列研究。
J Med Internet Res. 2022 Aug 9;24(8):e38082. doi: 10.2196/38082.

引用本文的文献

1
Predicting 30-day hospital readmissions using ClinicalT5 with structured and unstructured electronic health records.使用ClinicalT5结合结构化和非结构化电子健康记录预测30天再入院情况。
PLoS One. 2025 Sep 2;20(9):e0328848. doi: 10.1371/journal.pone.0328848. eCollection 2025.
2
Clinical frailty scale at ICU discharge predicts ICU readmission and post-ICU mortality: A retrospective single-center study.重症监护病房出院时的临床衰弱量表可预测再次入住重症监护病房及重症监护病房后的死亡率:一项回顾性单中心研究。
Medicine (Baltimore). 2025 Jun 20;104(25):e42955. doi: 10.1097/MD.0000000000042955.
3
Validation of the inadequate delivery of oxygen index in an adult cardiovascular intensive care unit.

本文引用的文献

1
Two-Step Approach for Occupancy Estimation in Intensive Care Units Based on Bayesian Optimization Techniques.基于贝叶斯优化技术的重症监护病房入住率两步估计法。
Sensors (Basel). 2023 Jan 19;23(3):1162. doi: 10.3390/s23031162.
2
Piloting a Survey-Based Assessment of Transparency and Trustworthiness with Three Medical AI Tools.使用三款医学人工智能工具对透明度和可信度进行基于调查的评估试点。
Healthcare (Basel). 2022 Sep 30;10(10):1923. doi: 10.3390/healthcare10101923.
3
Ethical Risk Factors and Mechanisms in Artificial Intelligence Decision Making.
成人心血管重症监护病房中氧输送指数不足的验证
JTCVS Open. 2024 Sep 12;22:354-361. doi: 10.1016/j.xjon.2024.09.006. eCollection 2024 Dec.
4
Digital health interventions in adult intensive care and recovery after critical illness to promote survivorship care.成人重症监护及危重症康复中的数字健康干预措施,以促进生存护理。
J Intensive Care Soc. 2025 Jan 4;26(1):96-104. doi: 10.1177/17511437241311105. eCollection 2025 Feb.
5
PSO-XnB: a proposed model for predicting hospital stay of CAD patients.PSO-XnB:一种用于预测冠心病患者住院时间的提议模型。
Front Artif Intell. 2024 May 3;7:1381430. doi: 10.3389/frai.2024.1381430. eCollection 2024.
6
Artificial intelligence to predict bed bath time in Intensive Care Units.人工智能预测重症监护病房的沐浴时间。
Rev Bras Enferm. 2024 Feb 26;77(1):e20230201. doi: 10.1590/0034-7167-2023-0201. eCollection 2024.
7
Evaluation and Treatment of Obesity and Its Comorbidities: 2022 Update of Clinical Practice Guidelines for Obesity by the Korean Society for the Study of Obesity.肥胖症及其合并症的评估与治疗:韩国肥胖研究学会2022年肥胖临床实践指南更新
J Obes Metab Syndr. 2023 Mar 30;32(1):1-24. doi: 10.7570/jomes23016. Epub 2023 Mar 22.
人工智能决策中的伦理风险因素与机制
Behav Sci (Basel). 2022 Sep 16;12(9):343. doi: 10.3390/bs12090343.
4
Using Bayesian Optimization and Wavelet Decomposition in GPU for Arterial Blood Pressure Estimation.基于 GPU 的贝叶斯优化和小波分解在动脉血压估计中的应用。
Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:1012-1015. doi: 10.1109/EMBC48229.2022.9871020.
5
Using Explainable Machine Learning to Improve Intensive Care Unit Alarm Systems.使用可解释机器学习来改进重症监护病房警报系统。
Sensors (Basel). 2021 Oct 27;21(21):7125. doi: 10.3390/s21217125.
6
Explainable Machine Learning on AmsterdamUMCdb for ICU Discharge Decision Support: Uniting Intensivists and Data Scientists.用于重症监护病房出院决策支持的阿姆斯特丹大学医学中心数据库可解释机器学习:重症医学专家与数据科学家的联合
Crit Care Explor. 2021 Sep 10;3(9):e0529. doi: 10.1097/CCE.0000000000000529. eCollection 2021 Sep.
7
A Clinical Decision Web to Predict ICU Admission or Death for Patients Hospitalised with COVID-19 Using Machine Learning Algorithms.一种使用机器学习算法预测因 COVID-19 住院患者入住 ICU 或死亡的临床决策网络。
Int J Environ Res Public Health. 2021 Aug 17;18(16):8677. doi: 10.3390/ijerph18168677.
8
Moving from bytes to bedside: a systematic review on the use of artificial intelligence in the intensive care unit.从字节到床边:人工智能在重症监护病房中的应用的系统评价。
Intensive Care Med. 2021 Jul;47(7):750-760. doi: 10.1007/s00134-021-06446-7. Epub 2021 Jun 5.
9
An explainable machine learning algorithm for risk factor analysis of in-hospital mortality in sepsis survivors with ICU readmission.一种用于分析脓毒症幸存者再次入住重症监护病房时院内死亡风险因素的可解释机器学习算法。
Comput Methods Programs Biomed. 2021 Jun;204:106040. doi: 10.1016/j.cmpb.2021.106040. Epub 2021 Mar 7.
10
Predicting Readmission to Intensive Care After Cardiac Surgery Within Index Hospitalization: A Systematic Review.心脏手术后再次入住重症监护病房的预测:系统评价。
J Cardiothorac Vasc Anesth. 2021 Jul;35(7):2166-2179. doi: 10.1053/j.jvca.2021.02.056. Epub 2021 Mar 1.