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2012年至2020年间心内科病房接受冠状动脉造影患者主动脉内球囊反搏使用情况的回顾性分析

Retrospective Analysis of Intra-Aortic Balloon Pump Use in Cardiology Ward Patients Undergoing Coronary Angiography between 2012 and 2020.

作者信息

Bochenek Tomasz, Sowula Patrycja, Rodak Małgorzata, Rybicka-Musialik Anna, Gruchlik Bartosz, Mizia-Stec Katarzyna

机构信息

First Department of Cardiology, School of Medicine in Katowice, Medical University of Silesia, 40055 Katowice, Poland.

Upper-Silesian Medical Center, 40635 Katowice, Poland.

出版信息

J Clin Med. 2023 Feb 16;12(4):1567. doi: 10.3390/jcm12041567.

DOI:10.3390/jcm12041567
PMID:36836102
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9962021/
Abstract

We aimed to evaluate the rate and risk factors of in-hospital mortality in patients undergoing coronary angiography/angioplasty with IABP use as support. We included 214 patients (mean age: 67.5 ± 7.5 years, M/F: 143/71) with an IABP used as the periprocedural support between 2012 and 2020. The main indications for an IABP were cardiogenic shock (143 pts; 66.8%: 55 survivors (51.9%)/88 non-survivors (81.5%); < 0.001) and infarction with an initial significant impairment of ventricular function (34 pts; 15.9%: 21 (19.8%)/13 (12%); = 0.12). In-hospital death was the endpoint of this study. In-hospital death occurred in 108 (50.5%, M/F: 69.4%/30.6%) patients. The mean hospitalization time was 7 days (2-13); deaths occurred more frequently on the first day after the procedure (1 (1-3 days) vs. 3 (1-8), < 0.001); and the mean hospitalization time was 2 days (1-6) for non-survivors vs. 11 days (7-17) for survivors ( < 0.001). Regarding the patients who did not survive, they were older (69 vs. 66.5, = 0.043), their LVEF was lower (0-15%: 15 (13.9%) vs. 12 (11.3%); 16-40%: 73 (67.6%) vs. 65 (61.3%); >40%: 14 (13%) vs. 29 (27.4%); = 0.007), and hyperlipidemia was less common (30 (27.8%) vs. 55 (51.9%) pts, = 0.001) than in those who survived. The IABP is still a method for cardiac support; however, mortality limits its use.

摘要

我们旨在评估以主动脉内球囊反搏(IABP)作为支持进行冠状动脉造影/血管成形术患者的院内死亡率及危险因素。我们纳入了2012年至2020年间214例(平均年龄:67.5±7.5岁,男/女:143/71)将IABP用作围手术期支持的患者。IABP的主要适应证为心源性休克(143例患者;66.8%:55例存活者(51.9%)/88例非存活者(81.5%);P<0.001)以及初始心室功能严重受损的梗死(34例患者;15.9%:21例(19.8%)/13例(12%);P = 0.12)。院内死亡是本研究的终点。108例(50.5%,男/女:69.4%/30.6%)患者发生院内死亡。平均住院时间为7天(2 - 13天);死亡更频繁地发生在术后第一天(1例(1 - 3天)对3例(1 - 8天),P<0.001);非存活者的平均住院时间为2天(1 - 6天),而存活者为11天(7 - 17天)(P<0.001)。对于未存活的患者,他们年龄更大(69岁对66.5岁,P = 0.043),左心室射血分数(LVEF)更低(0 - 15%:15例(13.9%)对12例(11.3%);16 - 40%:73例(67.6%)对65例(61.3%);>40%:14例(13%)对29例(27.4%);P = 0.007),且高脂血症比存活者更少见(30例(27.8%)对55例(51.9%)患者,P = 0.001)。IABP仍是一种心脏支持方法;然而,死亡率限制了其应用。

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本文引用的文献

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Impact of timing of intraaortic balloon counterpulsation on mortality in cardiogenic shock - a subanalysis of the IABP-SHOCK II trial.主动脉内球囊反搏时机对心源性休克死亡率的影响——IABP-SHOCK II试验的亚分析
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Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock.血管内微型轴流左心室辅助装置与主动脉内球囊泵在急性心肌梗死合并心源性休克患者中的应用与院内死亡率和大出血的关系。
JAMA. 2020 Feb 25;323(8):734-745. doi: 10.1001/jama.2020.0254.
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