Community Health Sciences Department, College of Applied Medical Sciences, King Saud University, Riyadh 11362, Saudi Arabia.
Department of Medicine, College of Medicine, King Saud University, Riyadh 12372, Saudi Arabia.
Nutrients. 2023 Feb 10;15(4):897. doi: 10.3390/nu15040897.
The Global Leadership Initiative on Malnutrition (GLIM) is a new approach established for the assessment of malnutrition. This study aimed to validate the GLIM for the diagnosis of malnutrition in patients with type 2 diabetes mellitus (T2DM) in Saudi Arabia, using the Subjective Global Assessment (SGA) as a reference. In addition, the association between the GLIM criteria and vascular complications in those patients was examined. A cross-sectional study was conducted on 101 patients with T2DM. The level of agreement between the GLIM and SGA tools was calculated using the kappa coefficient (κ). A receiver operating characteristic curve was used to determine the sensitivity and specificity of the GLIM. In addition, binary logistic regression was performed to investigate the association between each GLIM criterion and T2DM vascular complications. According to both the GLIM and the SGA, malnutrition was found in 15.8% and 17.8% of patients, respectively. The GLIM criteria achieved a very good level of accuracy (AUC = 0.877). The agreement between the tools was substantial (κ = 0.778). The 'disease/inflammation' criterion of the GLIM was significantly associated with macrovascular complications. To conclude, the GLIM criteria for diagnosis of malnutrition presented satisfactory levels of validity, and as such are acceptable for assessing the nutritional status of patients with T2DM.
全球营养不良领导倡议 (GLIM) 是一种新的营养不良评估方法。本研究旨在通过主观全面评估 (SGA) 作为参考,验证 GLIM 在沙特阿拉伯 2 型糖尿病 (T2DM) 患者中的营养不良诊断价值。此外,还检查了 GLIM 标准与这些患者血管并发症之间的关系。对 101 例 T2DM 患者进行了横断面研究。使用 Kappa 系数 (κ) 计算 GLIM 和 SGA 工具之间的一致性水平。使用受试者工作特征曲线确定 GLIM 的灵敏度和特异性。此外,还进行了二元逻辑回归分析,以研究每个 GLIM 标准与 T2DM 血管并发症之间的关系。根据 GLIM 和 SGA,营养不良分别在 15.8%和 17.8%的患者中发现。GLIM 标准具有非常高的准确性 (AUC = 0.877)。两种工具之间的一致性很高 (κ = 0.778)。GLIM 的“疾病/炎症”标准与大血管并发症显著相关。总之,GLIM 用于营养不良诊断的标准具有令人满意的有效性水平,因此可用于评估 T2DM 患者的营养状况。