CNR Institute of Neuroscience, 35127 Padova, Italy.
Department of Obstetrics and Gynaecology, Medical University of Vienna, 1090 Vienna, Austria.
Nutrients. 2022 Apr 29;14(9):1864. doi: 10.3390/nu14091864.
Sarcopenia is emerging as a severe complication in type 2 diabetes (T2DM). On the other hand, it has been documented that nutritional aspects, such as insufficient protein or total energy intake, increase sarcopenia risk. The analysis of body composition is a relevant approach to assess nutritional status, and different techniques are available. Among such techniques, bioelectrical impedance analysis (BIA) is particularly interesting, since it is non-invasive, simple, and less expensive than the other techniques. Therefore, we conducted a review study to analyze the studies using BIA for body composition analysis in T2DM patients with sarcopenia or at risk of catching it. Revised studies have provided important information concerning relationships between body composition parameters (mainly muscle mass) and other aspects of T2DM patients' conditions, including different comorbidities, and information on how to avoid muscle mass deterioration. Such relevant findings suggest that BIA can be considered appropriate for body composition analysis in T2DM complicated by sarcopenia/muscle loss. The wide size of the patients' cohort in many studies confirms that BIA is convenient for clinical applications. However, studies with a specific focus on the validation of BIA, in the peculiar population of patients with T2DM complicated by sarcopenia, should be considered.
肌少症正在成为 2 型糖尿病(T2DM)的一种严重并发症。另一方面,已有文献记录表明,营养方面的问题,如蛋白质或总能量摄入不足,会增加肌少症的风险。人体成分分析是评估营养状况的一种相关方法,有多种技术可供选择。在这些技术中,生物电阻抗分析(BIA)特别有趣,因为它是非侵入性的、简单的,并且比其他技术更便宜。因此,我们进行了一项综述研究,分析了使用 BIA 进行肌少症或有肌少症风险的 T2DM 患者身体成分分析的研究。经过修订的研究提供了重要信息,涉及身体成分参数(主要是肌肉质量)与 T2DM 患者病情的其他方面之间的关系,包括不同的合并症,以及如何避免肌肉质量恶化的信息。这些相关发现表明,BIA 可用于分析伴有肌少症/肌肉损失的 T2DM 患者的身体成分。许多研究中患者队列的广泛规模证实了 BIA 非常适合临床应用。然而,应该考虑针对 T2DM 合并肌少症患者这一特殊人群的 BIA 验证的专门研究。