Sugaya K, Matsuyama K, Takakusaki K, Mori S
Department of Physiology (2nd Division), Asahikawa Medical College, Japan.
Neurosci Lett. 1987 Sep 23;80(2):197-201. doi: 10.1016/0304-3940(87)90653-7.
In an acute decerebrate cat, electrical stimulation of the pontine micturition center (PMC) resulted in micturition. Carbachol injection into the PMC also resulted in micturition. The pattern of changes in bladder pressure and the sphincter activity observed during carbachol-induced micturition was almost identical to that observed during reflex micturition. The injection site corresponded to the nucleus locus coeruleus alpha (LC alpha). These results suggest that activation of cholinoceptive neurons in the LC alpha presumably becomes a trigger to recruit any one of a number of neuronal circuits involved in micturition.
在急性去大脑猫中，电刺激脑桥排尿中枢（PMC）会导致排尿。向PMC注射卡巴胆碱也会导致排尿。在卡巴胆碱诱导的排尿过程中观察到的膀胱压力和括约肌活动的变化模式与反射性排尿过程中观察到的几乎相同。注射部位对应于蓝斑α核（LCα）。这些结果表明，LCα中胆碱能感受神经元的激活可能成为触发参与排尿的众多神经回路中任何一个的诱因。
