Department of Internal Medicine, Bulancak State Hospital, Giresun, Turkey.
Department of Gastroenterology, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey.
Turk J Gastroenterol. 2023 Feb;34(2):140-147. doi: 10.5152/tjg.2023.22514.
Mesenteric panniculitis is a chronic inflammatory process seen in mesenteric tissue. The purpose of this study was to assess the prevalence, clinical, laboratory, and radiological findings, and malignancy in patients diagnosed with mesenteric panniculitis using computed tomography.
A total of 716 patients with mesenteric panniculitis were retrospectively evaluated by screening all computed tomography scans performed between January 2005 and December 2018.
Among 65 278 patients undergoing CT, 716 were diagnosed with mesenteric panniculitis. The prevalence of mesenteric panniculitis was 1.1%. The mean age was 56 ± 14 (20-91) years. The malignant and nonmalignant groups comprised 354 (49.4%) and 362 (50.6%) patients, respectively. The mean age of the malignant group was significantly higher than the nonmalignant group (P < .001). The most common malignancy was breast cancer (12.2%). A history of abdominal surgery was present in 179 (25%) patients with mesenteric panniculitis and it is higher in the malignant group than the nonmalignant group (128 [36.1%], 51 [14%], respectively, P < .001). Mean hemoglobin level and leukocyte count were lower in the malignant group than in the nonmalignant group (P < .001, P < .001, respectively). The mean erythrocyte sedimentation rate was higher in the malignant group than in the nonmalignant group (P = .030). Radiological criterion 2 was less common and radiological criterion 5 was more common in the malignant group than the nonmalignant group (91.0%, 96.4%, P = .004; 35.9%, 27.1%, respectively, P = .011).
It is recommended to conduct research for malignancy in patients with mesenteric panniculitis, especially in the presence of clinical, laboratory, and radiological findings with high-risk features.
肠系膜脂膜炎是一种发生在肠系膜组织中的慢性炎症过程。本研究的目的是评估通过计算机断层扫描（CT）诊断为肠系膜脂膜炎的患者的患病率、临床、实验室和影像学表现以及恶性肿瘤。
通过筛选 2005 年 1 月至 2018 年 12 月期间进行的所有 CT 扫描，对 716 例肠系膜脂膜炎患者进行回顾性评估。
在 65278 例行 CT 的患者中，有 716 例被诊断为肠系膜脂膜炎。肠系膜脂膜炎的患病率为 1.1%。平均年龄为 56 ± 14（20-91）岁。恶性和非恶性组分别包括 354（49.4%）和 362（50.6%）例患者。恶性组的平均年龄明显高于非恶性组（P <.001）。最常见的恶性肿瘤是乳腺癌（12.2%）。肠系膜脂膜炎患者中有 179 例（25%）有腹部手术史，且恶性组高于非恶性组（分别为 128[36.1%]和 51[14%]，P <.001）。恶性组的平均血红蛋白水平和白细胞计数低于非恶性组（P <.001，P <.001）。恶性组的平均红细胞沉降率高于非恶性组（P =.030）。恶性组的影像学标准 2 较少见，影像学标准 5 较常见（91.0%、96.4%，P =.004；35.9%、27.1%，P =.011）。
建议对肠系膜脂膜炎患者进行恶性肿瘤研究，特别是存在高风险特征的临床、实验室和影像学表现时。
