Department of Surgery, Christchurch Hospital, University of Otago, Christchurch, New Zealand.
Dis Colon Rectum. 2012 Jul;55(7):806-9. doi: 10.1097/DCR.0b013e318252e286.
Mesenteric panniculitis is an inflammatory condition of mesenteric adipose tissue with characteristic features on abdominal CT imaging. Although its cause is unknown, it has been associated with malignancy.
The aim of this study was to determine the prevalence of malignancy in patients identified as having mesenteric panniculitis on CT imaging and to identify demographic, clinical, and radiological features that may predict an unknown underlying malignancy.
This study is a retrospective analysis of medical records and imaging.
This study was conducted at Christchurch Hospital, Canterbury District Health Board, New Zealand.
Individuals with mesenteric panniculitis on abdominal CT imaging performed between 2003 and 2010 were included.
One hundred eighteen (92 male; median age, 61 years; range, 20-88 years) patients were identified with mesenteric panniculitis. Malignancy was identified in 45 patients (38%) (34 male). The most common malignancies were colorectal (14), lymphoma (13), and urogenital tract (7). Malignancies were diagnosed after the detection of mesenteric panniculitis in 13 patients. Univariate analysis of demographic, clinical, and radiological features revealed that lymph node size >12 mm (relative risk 4.5 (CI 1.4-14.6); p = 0.0266) and the absence of the fat ring sign (relative risk 0.6 (0.3-1.1); p = 0.047) were associated with the subsequent diagnosis of malignancy in patients with mesenteric panniculitis.
This review was limited by its retrospective nature and the small number of individuals with diagnosis of malignancy after the detection of mesenteric panniculitis.
Mesenteric panniculitis is often associated with an underlying malignancy. In most cases, malignancy is diagnosed before mesenteric panniculitis. Lymph node size (>12 mm) and the absence of the fat ring sign were identified as predictors of subsequent diagnosis of malignancy in patients with mesenteric panniculitis. Identification of mesenteric panniculitis on imaging should prompt an awareness for possible malignancy in these patients.
肠系膜脂膜炎是一种肠系膜脂肪组织的炎症性疾病，在腹部 CT 成像中有特征性表现。尽管其病因不明，但它与恶性肿瘤有关。
本研究旨在确定在 CT 成像中诊断为肠系膜脂膜炎的患者中恶性肿瘤的患病率，并确定可能预测未知潜在恶性肿瘤的人口统计学、临床和影像学特征。
这是一项回顾性的病历和影像学分析研究。
这项研究在新西兰坎特伯雷地区卫生局基督城医院进行。
纳入了 2003 年至 2010 年间进行的腹部 CT 成像中诊断为肠系膜脂膜炎的患者。
共确定了 118 例（92 例男性；中位年龄 61 岁；范围 20-88 岁）肠系膜脂膜炎患者。45 例（38%）患者发现恶性肿瘤（34 例男性）。最常见的恶性肿瘤是结直肠（14 例）、淋巴瘤（13 例）和泌尿生殖道（7 例）。13 例患者在诊断为肠系膜脂膜炎后诊断出恶性肿瘤。对人口统计学、临床和影像学特征的单变量分析显示，淋巴结大小>12mm（相对风险 4.5（CI 1.4-14.6）；p=0.0266）和缺乏脂肪环征（相对风险 0.6（0.3-1.1）；p=0.047）与肠系膜脂膜炎患者随后诊断为恶性肿瘤相关。
本回顾性研究受到其回顾性性质和诊断为肠系膜脂膜炎后恶性肿瘤患者数量较少的限制。
肠系膜脂膜炎常与潜在恶性肿瘤相关。在大多数情况下，恶性肿瘤在肠系膜脂膜炎之前被诊断出来。淋巴结大小（>12mm）和缺乏脂肪环征被确定为肠系膜脂膜炎患者随后诊断为恶性肿瘤的预测指标。影像学上发现肠系膜脂膜炎应引起这些患者对可能存在恶性肿瘤的警惕。
