Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Jonas Lies v 65, Bergen 5021, Norway.
Family Physician, Arkaden Legekontor, Arkaden Legekontor, Sartorvegen 12, Straume 5353, Norway.
J Anal Toxicol. 2023 Apr 14;47(4):e44-e47. doi: 10.1093/jat/bkad014.
Gamma-hydroxybutyrate (GHB) is a central nervous system depressant that has gained popularity as an illicit recreational drug. We describe a case of an elderly woman who was found unconscious in her home. The paramedics initially suspected an intracranial incident. A head computed tomography was negative, as was the initial urinary drug screening. The diagnosis of GHB intoxication was made with the detection of GHB in a urine sample obtained 28-29 hours after the assumed time of intake. Our case underscores the importance of considering drug testing in a broad range of patients and shows that elderly patients may have an extended detection window of GHB.
γ-羟基丁酸（GHB）是一种中枢神经系统抑制剂，作为一种非法的娱乐性药物而广受欢迎。我们描述了一位老年女性在家中昏迷的病例。护理人员最初怀疑是颅内事件。头部计算机断层扫描结果为阴性，初始尿液药物筛查也是阴性。在摄入后 28-29 小时获得的尿液样本中检测到 GHB，从而做出 GHB 中毒的诊断。我们的病例强调了在广泛的患者中考虑药物检测的重要性，并表明老年患者可能有更长的 GHB 检测窗口。
