Guangdong Eye Institute, Department of Ophthalmology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University.
Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital.
Am Psychol. 2023 Nov;78(8):982-994. doi: 10.1037/amp0001143. Epub 2023 Feb 27.
Visual disabilities significantly impact an individual's mental health. Little is known about the prospective relationship between visual disabilities and anxiety disorders and the underlying effects of modifiable risk factors. Our analysis was based on 117,252 participants from the U.K. Biobank, with baseline data collected between 2006 and 2010. Habitual visual acuity was measured by a standardized logarithmic chart, and ocular disorders reported using questionnaires were collected at baseline. Incident hospitalized anxiety recorded using longitudinal linkage with hospital inpatient data, lifetime anxiety disorder, and current anxiety symptoms assessed by a comprehensive online mental health questionnaire were identified over a 10-year follow-up. After adjustments for confounding factors, one-line worse visual acuity (0.1 logarithm of the minimum angle of resolution [logMAR]) was associated with an increased risk of incident hospitalized anxiety (HR = 1.05, 95% CI = 1.01-1.08), lifetime anxiety disorder ( = 1.07, 95% CI [1.01-1.12]), and current anxiety scores (β = 0.028, 95% CI [0.002-0.054]). Besides poorer visual acuity, the longitudinal analysis also supported that each ocular disorder (including cataracts, glaucoma, macular degeneration, and diabetes-related eye disease) was significantly associated with at least two anxiety outcomes. Mediation analyses highlighted that subsequent onsets of eye diseases, especially cataracts, and lower socioeconomic status (SES) partly mediated the association between poorer visual acuity and anxiety disorders. This study demonstrates an overall association between visual disabilities and anxiety disorders in middle-aged and older adults. In particular, early interventions involving treatments for visual disabilities and effective psychological counseling services sensitive to socioeconomic status may help prevent anxiety in those living with poor vision. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
视力障碍会显著影响个体的心理健康。人们对视力障碍与焦虑症之间的前瞻性关系以及可改变的风险因素的潜在影响知之甚少。我们的分析基于英国生物库的 117252 名参与者，基线数据收集于 2006 年至 2010 年之间。习惯性视力通过标准化对数图表测量，在基线时使用问卷收集眼部疾病报告。通过与住院数据的纵向链接记录的新发病例住院焦虑症、终身焦虑症和通过全面在线心理健康问卷评估的当前焦虑症状在 10 年的随访中确定。在调整混杂因素后，视力每下降一行（0.1 个最小分辨角对数[logMAR]），新发病例住院焦虑症的风险增加（HR = 1.05，95%CI = 1.01-1.08）、终身焦虑症（ = 1.07，95%CI [1.01-1.12]）和当前的焦虑评分（β=0.028，95%CI [0.002-0.054]）。除了较差的视力外，纵向分析还支持每种眼部疾病（包括白内障、青光眼、黄斑变性和糖尿病相关眼病）与至少两种焦虑结果显著相关。中介分析强调，眼部疾病的后续发作，特别是白内障和较低的社会经济地位（SES），部分解释了较差视力与焦虑症之间的关联。这项研究表明，中年和老年人的视力障碍与焦虑症之间存在总体关联。特别是，早期干预包括针对视力障碍的治疗和针对社会经济地位敏感的有效心理咨询服务，可能有助于预防视力不佳者的焦虑症。（PsycInfo 数据库记录（c）2023 APA，保留所有权利）。
