Department of Computer Science and Engineering, Islamic University, Kushtia 7003, Bangladesh; Computational Biology and Bioinformatics Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon 16419, Gyeonggi-do, Republic of Korea.
School of Computer Science and Technology, University of Science and Technology of China (USTC), Hefei, Anhui, 230026, China.
Neural Netw. 2023 Apr;161:757-775. doi: 10.1016/j.neunet.2023.02.022. Epub 2023 Feb 22.
The monkeypox virus poses a new pandemic threat while we are still recovering from COVID-19. Despite the fact that monkeypox is not as lethal and contagious as COVID-19, new patient cases are recorded every day. If preparations are not made, a global pandemic is likely. Deep learning (DL) techniques are now showing promise in medical imaging for figuring out what diseases a person has. The monkeypox virus-infected human skin and the region of the skin can be used to diagnose the monkeypox early because an image has been used to learn more about the disease. But there is still no reliable Monkeypox database that is available to the public that can be used to train and test DL models. As a result, it is essential to collect images of monkeypox patients. The "MSID" dataset, short form of "Monkeypox Skin Images Dataset", which was developed for this research, is free to use and can be downloaded from the Mendeley Data database by anyone who wants to use it. DL models can be built and used with more confidence using the images in this dataset. These images come from a variety of open-source and online sources and can be used for research purposes without any restrictions. Furthermore, we proposed and evaluated a modified DenseNet-201 deep learning-based CNN model named MonkeyNet. Using the original and augmented datasets, this study suggested a deep convolutional neural network that was able to correctly identify monkeypox disease with an accuracy of 93.19% and 98.91% respectively. This implementation also shows the Grad-CAM which indicates the level of the model's effectiveness and identifies the infected regions in each class image, which will help the clinicians. The proposed model will also help doctors make accurate early diagnoses of monkeypox disease and protect against the spread of the disease.
猴痘病毒在我们从 COVID-19 中恢复的同时,构成了新的大流行威胁。尽管猴痘的致命性和传染性不如 COVID-19,但每天仍有新的病例记录。如果不做好准备,很可能会引发全球大流行。深度学习 (DL) 技术在医学成像领域已经显示出了识别一个人患有什么疾病的潜力。可以使用感染猴痘的人类皮肤和皮肤区域的图像来早期诊断猴痘,因为已经使用图像来更深入地了解这种疾病。但是,仍然没有可供公众使用的可靠的猴痘数据库,无法用于训练和测试 DL 模型。因此,收集猴痘患者的图像至关重要。“MSID”数据集,即“猴痘皮肤图像数据集”的简称,是为本研究开发的,任何人都可以免费使用,并可以从 Mendeley Data 数据库下载。使用这个数据集的图像,可以更有信心地构建和使用 DL 模型。这些图像来自各种开源和在线资源,可以在没有任何限制的情况下用于研究。此外,我们提出并评估了一个名为 MonkeyNet 的基于修改后的 DenseNet-201 深度学习的 CNN 模型。该研究使用原始和增强数据集提出了一个深度卷积神经网络,能够分别以 93.19%和 98.91%的准确率正确识别猴痘疾病。该实现还展示了 Grad-CAM,它指示了模型的有效性水平,并识别出每个类别图像中的感染区域,这将有助于临床医生。该提出的模型还将帮助医生对猴痘疾病做出准确的早期诊断,并防止疾病的传播。