Zeng Dequan, Wang Jie, Xiao Bin, Zhang Hao, Ma Xingming
School of Health Management, Xihua University, Chengdu 610039, China.
Health Promotion Center, Xihua University, Chengdu 610039, China.
Vaccines (Basel). 2023 Jan 29;11(2):295. doi: 10.3390/vaccines11020295.
Coronavirus disease 2019 (COVID-19), beginning in December 2019, has spread worldwide, leading to the death of millions. Owing to the absence of definitive treatment, vaccination against COVID-19 emerged as an effective strategy against the spread of the pandemic. Acceptance of the COVID-19 vaccine has advanced considerably, and vaccine-related research has significantly increased over the past three years. This study aimed to evaluate the content and external characteristics of COVID-19 vaccine-related literature for tracking research trends related to the global COVID-19 vaccine with the means of bibliometrics and visualization maps. A total of 18,285 records in 3499 journals were retrieved in the Web of Science Core Collection database and included in the final analysis. China was the first to focus on COVID-19 vaccine research, while European and American countries started late but developed rapidly. The USA and the UK are the top contributors to COVID-19 vaccine development, with the largest number of publications. The University of Washington and Harvard Medical School were the leading institutions, while Krammer, F. from Icahn School of Medicine at Mount Sinai was the author most active and influential to the topic. had the highest number of citations and the highest TLS, and was the most cited and influential journal in the field of COVID-19 vaccine research. COVID-19 vaccine research topics and hotspots focused on populations' attitudes towards vaccination, immunity-related information analysis of spike proteins, the effectiveness and side effects of the COVID-19 vaccine, and the public management of epidemic transmission. The findings of this study provide the global status, research hotspots and potential trends in the field of COVID-19 vaccine research, which will assist researchers in mastering the knowledge structure, and evaluating and guiding future developmental directions of COVID-19 vaccine.
2019年冠状病毒病（COVID-19）自2019年12月开始在全球范围内传播，导致数百万人死亡。由于缺乏确切的治疗方法，针对COVID-19的疫苗接种成为对抗该大流行病传播的有效策略。在过去三年里，对COVID-19疫苗的接受度有了显著提高，与疫苗相关的研究也大幅增加。本研究旨在通过文献计量学和可视化地图的方法，评估COVID-19疫苗相关文献的内容和外部特征，以追踪全球COVID-19疫苗的研究趋势。在科学网核心合集数据库中检索到3499种期刊上的18285条记录，并纳入最终分析。中国是最早关注COVID-19疫苗研究的国家，而欧美国家起步较晚但发展迅速。美国和英国是COVID-19疫苗研发的最大贡献者，发表的论文数量最多。华盛顿大学和哈佛医学院是领先机构，而西奈山伊坎医学院的克拉默·F.是对该主题最活跃、最有影响力的作者。拥有最高的被引次数和最高的TLS，是COVID-19疫苗研究领域被引次数最多、最有影响力的期刊。COVID-19疫苗研究主题和热点集中在人群对疫苗接种的态度、刺突蛋白的免疫相关信息分析、COVID-19疫苗的有效性和副作用以及疫情传播的公共管理。本研究结果提供了COVID-19疫苗研究领域的全球现状、研究热点和潜在趋势，将有助于研究人员掌握知识结构，评估和指导COVID-19疫苗未来的发展方向。
