Scardia Annalaura, Laricchiuta Pietro, Stabile Marzia, Acquafredda Claudia, Lacitignola Luca, Uva Annamaria, Crovace Antonio, Staffieri Francesco
Ph.D. Course in "Tissues and Organs Transplantations and Cellular Therapies", D.E.O.T., University of Bari, 70121 Bari, Italy.
Section of Veterinary Clinics and Animal Production, D.E.O.T., University of Bari, 70123 Bari, Italy.
Vet Sci. 2023 Feb 15;10(2):158. doi: 10.3390/vetsci10020158.
The study aims to describe the anesthetic and airway management of baboons undergoing laparoscopic salpingectomy with a laryngeal mask airway (LMA) device. Eleven baboons received tiletamine-zolazepam and medetomidine; anesthesia was induced with propofol. An LMA was positioned for oxygen and isoflurane administration in spontaneous respiration. Heart rate (HR), mean arterial pressure (MAP), respiratory rate (RR), end tidal carbon dioxide (EtCO), minute volume (MV), and peripheral hemoglobin oxygen saturation (SpO) were recorded before (PREPP) and immediately after abdomen insufflation (PP1), at 10 (PP2), 20 (PP3), and 30 (PP4) minutes during pneumoperitoneum, and after (POSTPP) pneumoperitoneum. The respiratory rate was significantly higher at all times compared to PREPP. The end tidal carbon dioxide concentration was significantly higher at PP2, PP3, PP4, and POSTPP, compared to the previous times. The higher values for RR and EtCO were registered at PP4: 22.7 (95% CI 17.6-27.8) breaths/min and 57.9 (95% CI 51.9-63.8) mmHg, respectively. The minute volume was significantly higher at PP4 and POSTPP compared to the other times. The higher value for MV was registered at POSTPP (269.1 (95% CI 206.1-331.8) mL/kg/min). This protocol is suitable for baboons undergoing laparoscopic salpingectomy. The LMA was easy to insert and allowed for good ventilation, gas exchange, and delivery of the anesthetic in spontaneous breathing baboons.
本研究旨在描述使用喉罩气道(LMA)装置对接受腹腔镜输卵管切除术的狒狒进行麻醉和气道管理的情况。11只狒狒接受了替来他明-唑拉西泮和美托咪定;麻醉诱导使用丙泊酚。放置LMA以在自主呼吸时给予氧气和异氟烷。记录心率(HR)、平均动脉压(MAP)、呼吸频率(RR)、呼气末二氧化碳(EtCO)、分钟通气量(MV)和外周血红蛋白氧饱和度(SpO),分别在腹部充气前(PREPP)、腹部充气后即刻(PP1)、气腹期间10分钟(PP2)、20分钟(PP3)和30分钟(PP4)以及气腹后(POSTPP)。与PREPP相比,所有时间的呼吸频率均显著更高。与前一时刻相比,PP2、PP3、PP4和POSTPP时的呼气末二氧化碳浓度显著更高。RR和EtCO的较高值出现在PP4:分别为22.7(95%可信区间17.6 - 27.8)次/分钟和57.9(95%可信区间51.9 - 63.8)mmHg。与其他时间相比,PP4和POSTPP时的分钟通气量显著更高。MV的较高值出现在POSTPP(269.1(95%可信区间206.1 - 331.8)mL/kg/分钟)。该方案适用于接受腹腔镜输卵管切除术的狒狒。LMA易于插入,并能在自主呼吸的狒狒中实现良好的通气、气体交换和麻醉药输送。