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糖尿病患者的药物依从性及自我护理实践中的环境障碍:印度东部一家生活方式诊所的横断面研究

Medication adherence and environmental barriers to self-care practice among people with diabetes: A cross-sectional study in a lifestyle clinic in eastern India.

作者信息

Ghosh Archisman, Banerjee Saugat, Dalai Chanchal K, Chaudhuri Sirshendu, Sarkar Kingsuk, Sarkar Deblina

机构信息

Intern, College of Medicine & JNM Hospital, India.

Department of Community Medicine, College of Medicine & JNM Hospital, WB, India.

出版信息

J Taibah Univ Med Sci. 2023 Feb 3;18(5):909-916. doi: 10.1016/j.jtumed.2023.01.010. eCollection 2023 Oct.

Abstract

OBJECTIVE

The study was conducted to estimate the prevalence of non-adherence to medications among patients with type 2 diabetes attending a lifestyle clinic in a tertiary care hospital in West Bengal, India; to identify the environmental barriers to self-care practices, including diet, exercise, glucose testing and medication; and to identify the socio-demographic and environmental determinants of medication non-adherence.

METHODS

A cross-sectional study was performed among the patients with type 2 diabetes taking oral hypoglycemic drugs and attending a lifestyle clinic of a teaching hospital in 2021. The participants were interviewed in clinical settings via a structured questionnaire in the local language. Medication adherence was assessed with Morisky Medication Adherence Scale-8 (MMAS), and environmental barriers were assessed with the Environmental Barrier Assessment Scale (EBAS).

RESULTS

Among 178 participants, a high level of adherence (MMAS score 8.0) was found among 3 (1.7%) participants, and moderate adherence (MMAS score 6.0 to 7.75) was found among 67 (37.6%; 95% CI 30.3%, 44.9%) participants. The prevalence of non-adherence was 60.7% (95% CI: 53.4%, 68.0%). The overall mean barrier score was 134 (SD 13). All environmental barrier components were distributed equally among the predictor variables except the diet score, which was lower among men (mean difference 1.3; 95% CI: 0.04, 2.5) and people with higher education (mean difference 1.8; 95% CI: 0.6, 3.1).

CONCLUSION

The study indicated poor adherence to OHA in this population. Barriers to self-care practice and medication adherence were observed acrross all socio-economic strata. Poor medication adherence poses a major challenge to clinicians and public health experts in achieving treatment goals.

摘要

目的

本研究旨在估计印度西孟加拉邦一家三级护理医院生活方式诊所中2型糖尿病患者的药物治疗不依从率;确定自我护理行为(包括饮食、运动、血糖检测和药物治疗)的环境障碍;并确定药物治疗不依从的社会人口学和环境决定因素。

方法

2021年,对在一家教学医院生活方式诊所服用口服降糖药的2型糖尿病患者进行了一项横断面研究。通过当地语言的结构化问卷在临床环境中对参与者进行访谈。使用Morisky药物治疗依从性量表-8(MMAS)评估药物治疗依从性,使用环境障碍评估量表(EBAS)评估环境障碍。

结果

在178名参与者中,3名(1.7%)参与者的依从性较高(MMAS评分8.0),67名(37.6%;95%CI 30.3%,44.9%)参与者的依从性中等(MMAS评分6.0至7.75)。不依从率为60.7%(95%CI:53.4%,68.0%)。总体平均障碍评分为134(标准差13)。除饮食评分外,所有环境障碍成分在预测变量中分布均匀,饮食评分在男性中较低(平均差异1.3;95%CI:0.04,2.5),在受过高等教育的人群中较低(平均差异1.8;95%CI:0.6,3.1)。

结论

该研究表明该人群对口服降糖药的依从性较差。在所有社会经济阶层中均观察到自我护理行为和药物治疗依从性的障碍。药物治疗依从性差对临床医生和公共卫生专家实现治疗目标构成了重大挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22e4/9958071/55dd32367927/gr1.jpg

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