Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio 1 Coppito, 67100, L'Aquila, Italy.
Department of Emergency Medicine, Ospedale "Felice Lotti", Pontedera, Italy.
Neurol Sci. 2023 Jun;44(6):1849-1853. doi: 10.1007/s10072-023-06712-0. Epub 2023 Feb 28.
Measures adopted to contain the spread of SARS-CoV-2 could have led to a reduction in the rate of non-COVID-19 infections. We assessed whether a similar reduction was present in patients with stroke.
We performed a hospital-based study nested in a prospective population-based registry. We compared prevalence of infections and in-hospital mortality in subjects admitted for acute stroke between the first pandemic year (study period, from March 2020 to February 2021) and the pre-pandemic year (control period, from March 2019 to February 2020). Infections were reported as pneumonia (PNA), urinary tract infections (UTI), and any infection (INF).
From the control (n = 677) to the study period (n = 520), the prevalence of INF decreased from 11.5 to 4.6% (p < 0.001) and that of PNA decreased from 6.9 to 2.5% (p = 0.001). No changes in in-hospital mortality and length of hospital stay were observed between the two periods.
The observed reduction of in-hospital pneumonias in patients with stroke was likely attributable to the use of protective measures and limitation of hospital visits. Maintaining some of those measures in the long term may contribute to control infections in hospitalized patients with stroke.
为了遏制 SARS-CoV-2 的传播而采取的措施可能导致非 COVID-19 感染率降低。我们评估了这种情况是否也存在于中风患者中。
我们进行了一项基于医院的研究，嵌套在一个前瞻性的基于人群的登记研究中。我们比较了在第一波大流行年份（研究期间，从 2020 年 3 月至 2021 年 2 月）和大流行前年份（对照期间，从 2019 年 3 月至 2020 年 2 月）因急性中风入院的患者中感染和住院死亡率的情况。感染报告为肺炎（PNA）、尿路感染（UTI）和任何感染（INF）。
从对照期（n=677）到研究期（n=520），INF 的患病率从 11.5%降至 4.6%（p<0.001），PNA 的患病率从 6.9%降至 2.5%（p=0.001）。两个时期的住院死亡率和住院时间均无变化。
观察到中风患者住院肺炎的减少可能归因于保护措施的使用和医院探视的限制。在长期内维持其中一些措施可能有助于控制住院中风患者的感染。
