Jennison Toby, Ukoumunne Obi, Lamb Sallie, Sharpe Ian, Goldberg Andrew J
Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.
University Hospitals Plymouth NHS Trust, Plymouth, UK.
Bone Joint J. 2023 Mar 1;105-B(3):301-306. doi: 10.1302/0301-620X.105B3.BJJ-2022-0806.R1.
Despite the increasing numbers of ankle arthroplasties, there are limited studies on their survival and comparisons between different implants. The primary aim of this study was to determine the failure rates of primary ankle arthroplasties commonly used in the UK. A data linkage study combined National Joint Registry (NJR) data and NHS Digital data. The primary outcome of failure was defined as the removal or exchange of any components of the implanted device. Life tables and Kaplan-Meier survival charts were used to illustrate survivorship. Cox proportional hazards regression models were fitted to compare failure rates between 1 April 2010 and 31 December 2018. Overall, 5,562 primary ankle arthroplasties were recorded in the NJR. Linked data show a one-year survivorship of 98.8% (95% confidence interval (CI) 98.4% to 99.0%), five-year survival in 2,725 patients of 90.2% (95% CI 89.2% to 91.1%), and ten-year survival in 199 patients of 86.2% (95% CI 84.6% to 87.6%). The five-year survival for fixed-bearing implants was 94.3% (95% CI 91.3% to 96.3%) compared to 89.4% (95% CI 88.3% to 90.4%) for mobile-bearing implants. A Cox regression model for all implants with over 100 implantations using the implant with the best survivorship (Infinity) as the reference, only the STAR (hazard ratio (HR) 1.60 (95% CI 0.87 to 2.96)) and INBONE (HR 0.38 (95% CI 0.05 to 2.84)) did not demonstrate worse survival at three and five years. Ankle arthroplasties in the UK have a five-year survival rate of 90.2%, which is lower than recorded on the NJR, because we have shown that approximately one-third of ankle arthroplasty failures are not reported to the NJR. There are statistically significant differences in survival between different implants. Fixed-bearing implants appear to demonstrate higher survivorship than mobile-bearing implants.
尽管踝关节置换手术的数量不断增加,但关于其生存率以及不同植入物之间比较的研究却很有限。本研究的主要目的是确定英国常用的初次踝关节置换手术的失败率。一项数据关联研究将国家关节注册中心(NJR)的数据与英国国民医疗服务体系数字化数据相结合。失败的主要结局被定义为植入装置的任何部件被移除或更换。使用生命表和Kaplan-Meier生存图表来说明生存率。拟合Cox比例风险回归模型以比较2010年4月1日至2018年12月31日期间的失败率。总体而言,NJR记录了5562例初次踝关节置换手术。关联数据显示一年生存率为98.8%(95%置信区间(CI)98.4%至99.0%),2725例患者的五年生存率为90.2%(95%CI 89.2%至91.1%),199例患者的十年生存率为86.2%(95%CI 84.6%至87.6%)。固定平台植入物的五年生存率为94.3%(95%CI 91.3%至96.3%),而活动平台植入物为89.4%(95%CI 88.3%至90.4%)。对于所有植入量超过100例的植入物,以生存率最佳的植入物(Infinity)作为对照进行Cox回归模型分析,只有STAR(风险比(HR)1.60(95%CI 0.87至2.96))和INBONE(HR 0.38(95%CI 0.05至2.84))在三年和五年时未显示出更差的生存率。英国的踝关节置换手术五年生存率为90.2%,低于NJR记录的数值,因为我们已表明约三分之一的踝关节置换手术失败未上报至NJR。不同植入物之间的生存率存在统计学显著差异。固定平台植入物似乎比活动平台植入物表现出更高的生存率。