Suppr超能文献

超声引导下髋关节手术的关节周围神经组阻滞:一项比较罗哌卡因与罗哌卡因加地塞米松的随机对照试验研究

Ultrasound-Guided Pericapsular Nerve Group Block for Hip Surgery: A Randomized Controlled Trial Study Comparing Ropivacaine and Ropivacaine With Dexamethasone.

作者信息

Balasubramaniam Aswin, Kumar Naggaih Suresh, Tarigonda Sumanth, Madhusudhana Ravi

机构信息

Anaesthesiology, Sri Devaraj Urs Medical College, Kolar, IND.

出版信息

Cureus. 2023 Jan 27;15(1):e34261. doi: 10.7759/cureus.34261. eCollection 2023 Jan.

Abstract

BACKGROUND

Patients with hip fractures will be experiencing excruciating pain, which would prevent the ideal positioning of the patient for the neuraxial blockade. There is growing interest in using regional nerve blocks for pain in the elderly associated with a fractured hip. Pericapsular Nerve Group (PENG) block is gaining popularity as a provider of adequate analgesia in patients suffering from a hip fracture. The present study aimed to assess the effectiveness of PENG block using ropivacaine alone or ropivacaine with dexamethasone in reducing pain scores during patient positioning for the central neuraxial blockade and to compare the duration of postoperative analgesia.

MATERIALS AND METHODS

This randomized double-blinded study was conducted on patients posted for hip surgery under spinal anesthesia at a tertiary care referral hospital between January 2021 and May 2022. Twenty-eight patients (14 in each group) were randomly allocated to receive either group A (20 ml of 0.5% ropivacaine for PENG block) or Group B (20ml of 0.5% ropivacaine with 8mg Dexamethasone for PENG block) before patient positioning for subarachnoid block. Intra-operative hemodynamic variables, pain scores on a visual analog scale (VAS), at rest and with movement, before block, at the time of positioning for spinal anesthesia, time for first rescue analgesic request, and the total dosage of rescue analgesia in the first 24 hours after PENG block were measured.

RESULTS

Pain scores at rest and with movement at baseline and at the time of positioning for spinal anesthesia were significant within the groups (p< 0.01). The time for the first rescue analgesic requirement was significantly longer in group B (445.0 ±17.4 minutes) than in group A (388.9±19.0 minutes) (p<0.05). The mean average number of doses of rescue analgesia (Tramadol in milligrams) was significantly lower in group B (190 ± 60) than in group A patients (250 ± 70) (p<0.05).

CONCLUSION

The present study documented the effectiveness of PENG for patient positioning during the neuraxial blockade. Further, the addition of dexamethasone as an adjunct to ropivacaine yields a significantly longer duration of postoperative analgesia with a lower postoperative analgesic requirement.

摘要

背景

髋部骨折患者会经历剧痛,这会妨碍患者在进行神经轴阻滞时的理想体位摆放。使用区域神经阻滞来缓解老年髋部骨折相关疼痛的兴趣日益浓厚。关节囊周围神经组(PENG)阻滞作为为髋部骨折患者提供充分镇痛的方法,越来越受到欢迎。本研究旨在评估单独使用罗哌卡因或罗哌卡因联合地塞米松进行PENG阻滞在患者进行中枢神经轴阻滞体位摆放期间降低疼痛评分的有效性,并比较术后镇痛的持续时间。

材料与方法

本随机双盲研究于2021年1月至2022年5月在一家三级医疗转诊医院对接受脊髓麻醉下髋部手术的患者进行。28例患者(每组14例)在蛛网膜下腔阻滞患者体位摆放前被随机分配接受A组(20毫升0.5%罗哌卡因用于PENG阻滞)或B组(20毫升0.5%罗哌卡因加8毫克地塞米松用于PENG阻滞)。测量术中血流动力学变量、视觉模拟量表(VAS)上的疼痛评分,包括静息和活动时的评分、阻滞前、脊髓麻醉体位摆放时、首次要求使用补救镇痛药的时间以及PENG阻滞后24小时内补救镇痛药的总剂量。

结果

各组内基线时以及脊髓麻醉体位摆放时静息和活动时的疼痛评分均有显著差异(p<0.01)。B组首次要求使用补救镇痛药的时间(445.0±17.4分钟)显著长于A组(388.9±19.0分钟)(p<0.05)。B组补救镇痛药的平均剂量(以毫克计的曲马多)显著低于A组患者(190±60)(250±70)(p<0.05)。

结论

本研究证明了PENG阻滞在神经轴阻滞期间患者体位摆放方面的有效性。此外,在罗哌卡因中添加地塞米松作为辅助药物可显著延长术后镇痛时间,并降低术后镇痛需求。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验