Department of Public Health Medicine, Institute of Medicine, and Health Services Research and Development Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
Institute for Global Health Policy Research, National Center for Global Health and Medicine, Tokyo, Japan.
Eur J Nutr. 2023 Jun;62(4):1859-1866. doi: 10.1007/s00394-023-03111-1. Epub 2023 Mar 1.
The association between potato intake and risk of cardiovascular diseases is unknown. This study aimed to examine the association between potatoes intake and mortality from stroke and coronary heart disease among Japanese.
The study included 74,750 participants of the Japan Collaborative Cohort Study, aged 40-79, who were initially free of cardiovascular diseases or cancer at baseline (1988-1990) and provided information on their potato intake. Hazard ratios and 95% confidence intervals were estimated by fitting a Cox proportional hazards model according to the frequency of potatoes intake (0, 0.4, 1.5, 3.5 and 7 servings per week) adjusting for geographic location, age, body mass index, drinking status, smoking status, perceived mental stress, education level, walking time, dietary intakes of total energy, meat, fish, vegetables, fruit, dairy products, cakes, and salt.
Over a median of 19.2 years of follow-up, 4908 deaths from cardiovascular diseases were identified: 1019 from coronary heart diseases and 2153 from strokes (738 ischemic strokes and 495 hemorrhagic strokes). After adjustment for potential confounding factors, the hazard ratio of mortality from cardiovascular diseases for daily potato intake compared with no potato intake was 0.82 (95% confidence interval: 0.70, 0.95) among women, and 1.01 (0.88, 1.16) among men. Among women, the multivariable hazard ratios were 0.67 (0.48, 0.96) for coronary heart disease, 0.83 (0.66-1.05) for total stroke, 0.70 (0.43-1.15) for hemorrhagic stroke, and 0.75 (0.49-1.13) for ischemic stroke.
We found an inverse association of potato intake with mortality from total cardiovascular diseases, especially that from coronary heart disease, among Japanese women. To our knowledge, this is the first report to show an inverse association between potato intake and total cardiovascular diseases.
目前尚不清楚摄入土豆与心血管疾病风险之间的关系。本研究旨在探讨日本人群中摄入土豆与中风和冠心病死亡率之间的关系。
本研究纳入了日本协作队列研究中的 74750 名参与者，年龄在 40-79 岁之间，基线时（1988-1990 年）无心血管疾病或癌症，并提供了关于土豆摄入量的信息。根据土豆摄入量的频率（0、0.4、1.5、3.5 和 7 份/周），通过拟合 Cox 比例风险模型来估计风险比和 95%置信区间，同时调整了地理位置、年龄、体重指数、饮酒状况、吸烟状况、感知心理压力、教育水平、步行时间、总能量、肉类、鱼类、蔬菜、水果、乳制品、糕点和盐的饮食摄入。
在平均 19.2 年的随访期间，共发生了 4908 例心血管疾病死亡：1019 例死于冠心病，2153 例死于中风（738 例缺血性中风和 495 例出血性中风）。在校正了潜在混杂因素后，与不摄入土豆相比，女性每日摄入土豆与心血管疾病死亡率的风险比为 0.82（95%置信区间：0.70，0.95），男性为 1.01（0.88，1.16）。在女性中，多变量风险比分别为冠心病 0.67（0.48，0.96）、总中风 0.83（0.66-1.05）、出血性中风 0.70（0.43-1.15）和缺血性中风 0.75（0.49-1.13）。
我们发现日本女性摄入土豆与总心血管疾病死亡率呈负相关，尤其是冠心病死亡率。据我们所知，这是首次报告摄入土豆与总心血管疾病呈负相关。
