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SARS-CoV-2 导致抗生素消耗量激增,在大流行期间引发了一场无声的大流行。对 2022 年上半年意大利数据的回顾性分析。

SARS-CoV-2 caused a surge in antibiotic consumption causing a silent pandemic inside the pandemic. A retrospective analysis of Italian data in the first half of 2022.

机构信息

Pharmaceutical Department, Asl Napoli 3 Sud, Dell'amicizia street 22, 80035 Nola, Naples, Italy.

School of Pharmacy, University of Camerino, Via Sant'Agostino 1, 62032 Camerino, Italy.

出版信息

Ann Pharm Fr. 2023 Jun;81(4):627-635. doi: 10.1016/j.pharma.2023.02.003. Epub 2023 Feb 28.

Abstract

BACKGROUND

The phenomenon of antibiotic resistance shows no sign of stopping, despite global policies to combat it that have been in place for several years. The risk of forms of pathogenic microorganisms that are increasingly resistant to common antibiotics has led health authorities around the world to pay greater attention to the phenomenon. The worrying situation, has led to further recommendations from the World Health Organization (WHO) and national recommendations in Italy through the new National Plan against Antibiotic Resistance 2022-2025 (PNCAR 2022-2025).

AIM

This manuscript aims to raise the awareness of all health professionals to follow what is suggested by regulatory agencies and scientific societies.

METHOD

We conducted a retrospective study of antibiotic pharmacoutilization in Italy, in the Campania region at the Azienda Sanitaria Locale (ASL) Napoli 3 Sud, on consumption in the first half of 2022 in a population of more than 1 million people.

RESULT

The results indicate that consumption, based on defined daily doses (DDDs), is above the national average. Probably the COVID-19 pandemic has influenced this growth in prescriptions.

CONCLUSIONS

Our study suggests an informed and appropriate use of antibiotics, so as to embark on a virtuous path in the fight against antibiotic resistance.

摘要

背景

尽管多年来一直有全球政策来对抗抗生素耐药性现象,但这种现象并没有停止的迹象。致病微生物对普通抗生素的耐药性形式的风险增加,导致世界各地的卫生当局更加关注这一现象。这种令人担忧的情况,导致世界卫生组织(WHO)和意大利的国家建议进一步提出,通过新的 2022-2025 年国家抗生素耐药性计划(PNCAR 2022-2025)。

目的

本文旨在提高所有卫生专业人员对遵循监管机构和科学协会建议的认识。

方法

我们对意大利坎帕尼亚地区那不勒斯 3 南地方卫生机构(ASL)的抗生素药物利用情况进行了回顾性研究,研究了 2022 年上半年超过 100 万人口的消费情况。

结果

结果表明,基于规定日剂量(DDD)的消费高于全国平均水平。可能是 COVID-19 大流行影响了这种处方的增长。

结论

我们的研究表明,对抗生素的使用需要知情和适当,以便在对抗抗生素耐药性的斗争中走上良性道路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb01/9970653/182346d7b1e6/gr1_lrg.jpg

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