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儿童血铅水平以及家庭灰尘和水中的铅暴露——制定灰尘中铅的环境标准的依据

Children's blood lead and exposure to lead in household dust and water--a basis for an environmental standard for lead in dust.

作者信息

Laxen D P, Raab G M, Fulton M

机构信息

Department of Geology, University of Edinburgh, Scotland, United Kingdom.

出版信息

Sci Total Environ. 1987 Oct;66:235-44. doi: 10.1016/0048-9697(87)90091-x.

Abstract

Good quantitative evidence on the role of lead in household dust as a source of exposure to children has been lacking. A study of 495 children in Edinburgh, Scotland shows a significant relationship between lead in dust vacuumed from the floors of the children's homes and their blood lead levels. A multiple regression analysis incorporating drinking water and household dust estimates that a 1,000 micrograms g-1 increase in dust lead concentration would increase blood lead by 1.9 micrograms dl-1, for a child with the median population blood lead of 10.1 micrograms dl-1. Dust lead concentration is a more useful predictor of blood lead than lead loading. The sanding or blow-lamp stripping of old paint is found to be an important source of the higher household dust lead concentrations. Finally, the dust lead-blood lead relationship is used to derive a standard for lead in house dust, as no such standard exists for this exposure route.

摘要

关于家庭灰尘中的铅作为儿童接触源所起作用的充分定量证据一直缺乏。一项针对苏格兰爱丁堡495名儿童的研究表明,从儿童家中地板上吸尘得到的灰尘中的铅与他们的血铅水平之间存在显著关系。一项纳入饮用水和家庭灰尘的多元回归分析估计,对于血铅中位数为10.1微克/分升的儿童,灰尘铅浓度每增加1000微克/克,血铅将增加1.9微克/分升。灰尘铅浓度比铅负荷更能有效预测血铅水平。人们发现,对旧油漆进行打磨或用喷灯去除油漆是家庭灰尘中铅浓度升高的一个重要来源。最后,由于不存在针对这种接触途径的标准,因此利用灰尘铅与血铅的关系推导出了室内灰尘中铅的标准。

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