Lanphear B P, Weitzman M, Winter N L, Eberly S, Yakir B, Tanner M, Emond M, Matte T D
Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Am J Public Health. 1996 Oct;86(10):1416-21. doi: 10.2105/ajph.86.10.1416.
This study assessed the relationship between lead-contaminated house dust and urban children's blood lead levels.
A random-sample survey was used to identify and enroll 205 children, 12 to 31 months of age, who had resided in the same house since at least 6 months of age. Children's blood and household dust, water, soil, and paint were analyzed for lead, and interviews were conducted to ascertain risk factors for elevated blood lead (> or = 10 micrograms/dL).
Children's mean blood lead level was 7.7 micrograms/dL. In addition to dust lead loading (micrograms of lead per square foot), independent predictors of children's blood lead were Black race, soil lead levels, ingestion of soil or dirt, lead content and condition of painted surfaces, and water lead levels. For dust lead standards of 5 micrograms/sq ft, 20 micrograms/sq ft, and 40 micrograms/sq ft on noncarpeted floors, the estimated percentages of children having blood lead levels at or above 10 micrograms/dL were 4%, 15%, and 20%, respectively, after adjusting for other significant covariates.
Lead-contaminated house dust is a significant contributor to lead intake among urban children who have low-level elevations in blood lead. A substantial proportion of children may have blood lead levels of at least 10 micrograms/dL at dust lead levels considerably lower than current standards.
本研究评估了受铅污染的室内灰尘与城市儿童血铅水平之间的关系。
采用随机抽样调查,确定并纳入了205名年龄在12至31个月之间、自至少6个月大起就居住在同一房屋中的儿童。对儿童的血液以及家庭灰尘、水、土壤和油漆进行铅分析,并进行访谈以确定血铅升高(≥10微克/分升)的风险因素。
儿童的平均血铅水平为7.7微克/分升。除了灰尘铅负荷(每平方英尺的铅微克数)外,儿童血铅的独立预测因素包括黑人种族、土壤铅水平、摄入土壤或污垢、涂漆表面的铅含量和状况以及水铅水平。对于非铺地毯地板上灰尘铅标准分别为5微克/平方英尺、20微克/平方英尺和40微克/平方英尺的情况,在调整其他显著协变量后,估计血铅水平达到或高于10微克/分升的儿童百分比分别为4%、15%和20%。
受铅污染的室内灰尘是血铅水平轻度升高的城市儿童铅摄入的重要来源。在灰尘铅水平远低于现行标准的情况下,相当大比例的儿童血铅水平可能至少为10微克/分升。