Cortical Synaptic Mechanism for Chronic Pain and Anxiety in Parkinson's Disease.
作者信息
Zhou Zhaoxiang, Chen Qiyu, Liu Qin, Xu Pingyi, Lu Jingshan, Zhuo Min
机构信息
Department of Neurology, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510130, Guangdong Province, China.
Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an 710049, Shaanxi Province, China.
出版信息
J Transl Int Med. 2023 Jan 13;10(4):300-303. doi: 10.2478/jtim-2022-0046. eCollection 2022 Dec.
Abstract
摘要
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Oxytocin in the anterior cingulate cortex attenuates neuropathic pain and emotional anxiety by inhibiting presynaptic long-term potentiation.前扣带回皮层中的催产素通过抑制突触前长时程增强来减轻神经性疼痛和情绪焦虑。
Cell Rep. 2021 Jul 20;36(3):109411. doi: 10.1016/j.celrep.2021.109411.
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Inhibition of calcium-stimulated adenylyl cyclase subtype 1 (AC1) for the treatment of neuropathic and inflammatory pain in adult female mice.抑制钙刺激的腺苷酸环化酶 1 型（AC1）治疗成年雌性小鼠的神经性和炎性疼痛。
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